UC Berkeley intellectual property spinouts commercializing innovations in Medical Therapeutics.
4D Molecular Therapeutics LLC
Addition Therapeutics
Addition is transforming genetic medicine by developing RNA-only therapeutics that PRINT™ any genetic element at specific safe harbor sites.
Kathy Collins, Jeremy John McIntyre,...Read more about Addition Therapeutics
Algen Biotechnologies
Algen Biotechnologies is building a next-generation, functional genomics-based platform for the discovery of novel therapeutics for cancers with high unmet need. Algen’s research group focuses on developing and applying novel functional genomics technologies to address...Read more about Algen Biotechnologies
Amber Bio
A biotechnology company offering genetic medicine through biologically inspired design. The company offers gene editing modalities using multi-kilobase RNA writing to easily reach previously undruggable diseases, enabling medical researchers to easily develop independent...Read more about Amber Bio
Ambrx Inc.
Ansa Biotechnologies
With synthetic DNA fueling innovation in biological research, therapeutics, diagnostics, and biomanufacturing, there is an urgent need for faster and more accurate DNA synthesis. Currently, DNA is manufactured via a chemical method that has remained essentially unchanged for 35...Read more about Ansa Biotechnologies
Apertor Pharmaceuticals
Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational
...Read more about Apertor PharmaceuticalsArtris Therapeutics, Inc.
Artris Therapeutics was founded to identify and develop cancer therapeutics. The company was co-founded by UC Berkeley Professor of Chemical Biology and Molecular Therapeutics Daniel Nomura.
Timeline
AsparaGlue
AsparaGlue has developed a superglue-like medical adhesive for external wound closure and internal tissue adhesion. The proprietary technology is the world’s only biocompatible and biodegradable medical superglue.
Axent Biosciences
Axent Biosciences is a pre-clinical stage biotechnology company developing next generation stem cell therapies to address unmet medical needs in human diseases/disorders. The company was spun out of research discoveries in the lab of UC Berkeley Professor of Chemical and...Read more about Axent Biosciences
Azalea Therapeutics, Inc.
Azalea Therapeutics is an early-stage biotech startup on a mission to revolutionize genomic medicines. By designing vehicles that enable cell-specific delivery inside the body, the company aims to unlock precision therapeutics for genetic diseases and unleash the promise of...Read more about Azalea Therapeutics, Inc.
Berkeley BioSciences Inc.
Berkeley BioSciences, Inc. is a molecular immunology and oncology company with two divisions: biopharmaceutical and nutraceutical. It is researching and developing therapeutics and nutritional products based on patented...Read more about Berkeley BioSciences Inc.
Biotock
Development of treatments for age-related macular degeneration, a leading cause of blindness.
Monika Maria Haoui, Polina LishkoRead more about Biotock
CalGen Therapeutics
Developer of a therapeutic inhaled antisense technology designed to prevent and treat respiratory infections.
Kasper Karstensen, Sakari Kauppinen, Anders Michael Naar, Chi ZhuRead more about CalGen Therapeutics
CardioRegenx, Inc.
Developer of scanning electrochemical microscopy technology intended for clinical use.
TimelineJulius Guccione, Kevin Healy, Mark Ratcliffe, Samuel WallRead more about CardioRegenx, Inc.
Caribou Biosciences Inc.
Caribou Biosciences is a clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company’s genome-editing platform, including its Cas12a chRDNA technology, enables superior...Read more about Caribou Biosciences Inc.
CaseForge, Inc.
CaseForge produces personalized stabilizers for use in research and clinical imaging. These stabilizers interface with medical devices to precisely position the patient and eliminate motion, guaranteeing comfortable, fast, simple placement consistency...Read more about CaseForge, Inc.
Catalyst Biosciences, Inc.
Catalyst is a clinical-stage biopharmaceutical company leveraging exceptional science to discover and develop essential medicines. Catalyst is focused on creating and commercializing novel medicines to address serious medical conditions for patients...Read more about Catalyst Biosciences, Inc.
Catena Biosciences
Cantena Biosciences uncovered a novel protein conjugation method that can bring breakthroughs in biological therapeutics, autoimmune disorders, and vaccine development.
Catena’s technology allows the attachment of any two proteins together...Read more about Catena Biosciences
Cell-X
Editing T-cells with nanopore-electroporation to improve CRISPR-Cas9 editing capabilities.
YuHong Cao, Jennifer Doudna, Enbo Ma, Peidong Yang
Read more about Cell-XChiron Corporation
Chiron Corporation was an American biotechnology company engaged in biopharmaceuticals, vaccines and blood testing.
Dahlia Biosciences
Davis Allergy Research
Research tool to test genetically-engineered foods for allergens.
TimelineBob Buchanan, Gregorio Del Val, Oscar Frick, Hye Rim Jung, Boihon YeeRead more about Davis Allergy Research
Demetrix, Inc.
Demetrix, Inc. works with nature to make rare ingredients readily accessible to promote healthier and happier lives. By using microorganisms such as baker's yeast and fermentation combined with the most advanced biotechnology, data science and automation, Demetrix can produce...Read more about Demetrix, Inc.
DNA Nanobots, LLC
With a portfolio of existing IP, DNA Nanobots develops products for targeted therapeutics and functionalized gene delivery. We have a dual approach, building partnerships to provide development expertise in the functionalization of DNA nanotechnology with experience in Gene...Read more about DNA Nanobots, LLC
DNA Sciences, Inc.
While gene sequencing and gene expression technologies have become relatively industrialized, genetic analysis is a time-consuming, labor intensive, and rate-limiting step in drug discovery. DNA Sciences, Inc. removed this bottleneck by developing a high-throughput system that...Read more about DNA Sciences, Inc.
EditPep, Inc.
CRISPR therapies enabled by a simple, potent delivery platform. The biotechnology company creates a class of peptides capable of delivering CRISPR enzymes into clinically-relevant and previously untransfectable cell types, enabling clients to get CRISPR therapies.
...Read more about EditPep, Inc.Elenae Therapeutics
Applying antisense oligonucleotide technology to target coronaviruses, including SARS-CoV-2, the virus that causes COVID-19.
Anders Naar, Sakari KauppinenRead more about Elenae Therapeutics
Elon Therapeutics, Inc
Developing a gel pill to painlessly spray a vaccine into the cheek and reach cells in the underlying tissue to trigger a mucosal immune response.
Timeline 2015. Company founded InventorsKiana Aran, Kunwoo Lee, Dorian Liepmann, Niren Murthy, Jacobo...Read more about Elon Therapeutics, Inc
Epigenetic Gene Editing
Epigenetic Gene Editing is a gene editing tools company dedicated to improvements in CRISPR-Cas9 editing by providing a fusion protein kit to gene editing companies.
Formerly known as EPI-CRISPRx.
EscharaX Medical, Inc.
Tissue engineering to develop biometric materials for replacement arteries, nerve grafts, and healing wounds.
TimelineCraig Hashi, Ngan Fong Huang, Kyle Kurpinski, Song Li, Shyam PatelRead more about EscharaX Medical, Inc.
Evercrisp Biosciences
Evercrisp Biosciences is a biotechnology company engineering self-deliverable CRISPR genome editors intended to improve the area of oncology. The company focuses on the discovery and development of protein-based genome editors as therapeutics for multiple disease areas,
...Read more about Evercrisp BiosciencesExcellin Life Sciences, Inc.
Bionic chip technology that merges a living biological cell with electronic circuitry. This chip-based instrument allows for verification of transfection, enabling downstream assays and in situ detection of results, for use in basic research on cell death and drug toxicity....Read more about Excellin Life Sciences, Inc.
Exelixis, Inc.
Exelixis, Inc. is a commercially successful, oncology-focused biotechnology company that strives to accelerate the discovery, development and commercialization of new medicines for difficult-to-treat cancers. Following early work in model genetic systems, the
Frontier Medicines Corporation
Frontier Medicines was founded to develop medical treatments for currently "undruggable" diseases. The clinical stage precision medicine company pioneers medicines for genetically-defined patient populations in oncology and immunology, and plans to broaden its therapeutic...Read more about Frontier Medicines Corporation
GenEdit, Inc.
GenEdit develops innovative therapies through targeted delivery of genetic medicines. The GenEdit founders share the vision that recent scientific advancements in engineering CRISPR components and delivery vehicles offer a groundbreaking opportunity to develop safe and
...Read more about GenEdit, Inc.Geneditor Biosciences, Inc.
Geneditor Biosciences is a pre-clinical stage gene editing company focused on the treatment of rare cancers with unmet medical needs.
Jennifer DoudnaRead more about Geneditor Biosciences, Inc.
Genocea Biosciences, Inc.
Genocea finds targets of T cell responses to discover and develop life-changing medicines. The company created a pipeline of novel vaccine and immunotherapy programs that stimulate the T cell arm of the immune system, which is increasingly recognized as critical to generating...Read more about Genocea Biosciences, Inc.
GenoptX, LLC
A CRISPR-based gene editing company.
Formerly known as Syncodi.
Jennifer Doudna, Abraham Isser Flamholz, Dana Nadler, Benjamin Oakes, David Frank SavageRead more about GenoptX, LLC
Iaterion
Iaterion is a biopharma company developing novel therapeutics for women's health and diseases. The company develops targeted selective nuclear receptor drugs addressing multiple indications encountered by women and focuses on novel drugs as an alternative to menopausal hormone...Read more about Iaterion
iMEDD, Inc.
Drug delivery based on micro-engineering technology utilizing silicon microcapsules with nanofilters so that treatments can be controlled and targeted to particular cells and sites in the body.
The company licensed intellectual property that had been previously licensed...Read more about iMEDD, Inc.
Inapill
Inapill is developing novel therapeutics that tune immune cell metabolism (immunometabolism) to treat diseases caused by immune system overactivation and excessive inflammation.
Intellia
Intellia is a leading genome editing company focused on the development of proprietary, potentially curative therapeutics utilizing a recently developed biological tool known as the CRISPR/Cas9 system. Intellia leverages leading scientific expertise, clinical development...Read more about Intellia
Iris Micromedical, Inc.
Drug delivery based on microstructural devices that administer therapeutic agents to selected target sites for treatment.
Iris Micromedical was focused on the development of UC Berkeley Associate Professor of Engineering Mauro Ferrari's silicon particulate technology for...Read more about Iris Micromedical, Inc.
Juvena Therapeutics
Juvena Therapeutics is a venture-backed biopharma startup discovering novel protein-based therapeutics that promote tissue regeneration in the elderly and treat various age-related diseases. We are building a protein-based discovery platform by implementing an
Juvenon, Inc.
UC Berkeley scientists founded Juvenon to make their healthy aging breakthrough available to the public. The company's patented combination of natural micronutrients promotes a healthier, more energetic body and protects tissue from the toxic oxidants that increase with normal...Read more about Juvenon, Inc.
KaRNAteq, Inc.
KaRNATeq develops tools for RNA sequencing that are the next step forward in genomics. The enzymes developed by the company enable doctors and scientists to capture more information at reduced cost.
Kathleen CollinsRead more about KaRNAteq, Inc.
Laguna Bio
Developer of drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company specializes in providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of a
...Read more about Laguna BioLibraria, Inc.
Libraria Inc. is using computational techniques to discover new small-molecule drugs that can be administered orally. Its proprietary technology enables the company and its partners to leverage known molecular structures, chemistry protocols, and bioactivity data to
...Read more about Libraria, Inc.Lymphax, Inc.
Lymphax, Inc. is a therapeutics company treating ocular diseases and conditions.
Formerly known as NewVision Bioscience, Inc.
Lu Chen, Sammy Grimaldo, Meng Shi, Don YuenRead more about Lymphax, Inc.
Lyterian Therapeutics, Inc.
Lyterian Therapeutics is committed to developing transformative medicines for patients by co-opting physiologically relevant protein homeostatic mechanisms to regulate genetically-validated targets. Lyterian is derived from λυτήριος or lutḗrios, which means termination, healing...Read more about Lyterian Therapeutics, Inc.
Magnetic Insight
Magnetic Insight is developing solutions in Magnetic Particle Imaging (MPI), a ground-breaking technology that will overcome major deficiencies with current clinical and translational research imaging techniques.
Magnetic Insight Inc. was founded by one of the leading...Read more about Magnetic Insight
Magnetic Tides
Magnetic Tides has developed a new non-invasive brain stimulation (NIBS) system capable of modulating brain function more reliably and effectively than previously existing NIBS methods.
NIBS is used as a research tool to safely, transiently alter the excitability state...Read more about Magnetic Tides
Mammoth Biosciences
Mammoth’s vision is to provide a CRISPR-based platform on which an infinite number of tests can be built by both ourselves and our partners - democratizing access to an endless variety of tests for bio sensing in healthcare, as well as across industries such as agriculture,...Read more about Mammoth Biosciences
Mend Neuroscience, Inc.
Mend Neuroscience, Inc. is a therapeutics company treating cognitive disorders.
Daniela Kaufer, Alon Friedman, Luisa CacheauxRead more about Mend Neuroscience, Inc.
Mercator MedSystems Inc.
Mercator MedSystems, Inc. is a medical technology company focused on the treatment of peripheral artery disease utilizing its catheter-guided, microfluid infusion systems for site-specific, non-systemic delivery of therapeutic agents directly across any blood vessel. The...Read more about Mercator MedSystems Inc.
Mimesyn
Developing a novel class of molecules, aza-@-tides, that mimic the structural features of natural amino acids. These can be synthesized from amino acid precursors in either direction using standard peptide synthesis methods, facilitating the assembly of libraries...Read more about Mimesyn
Moment Bio
Developing curative therapies through versatile RNA targeting
Patrick David HsuRead more about Moment Bio
MRL Bio
The company is developing a unique drug delivery platform for tissue regeneration in acute and chronic wounds.
Timeline 2019. Company founded InventorsPhillip Messersmith, Jing Cheng, Ellen Heber-KatzRead more about MRL Bio
Nadaeon
Life sciences company.
Danica Chen, Hanzhi LuoRead more about Nadaeon
NanoNerve
NanoNerve is a medical device company developing tissue engineered implant solutions for neurosurgery. Their mission is to improve patient outcome by providing neurosurgeons with innovative solutions that encourage rapid neural tissue recovery and minimize complications. Using...Read more about NanoNerve
Narra Biosciences, LLC
Narra Biosciences develops anti-cancer therapeutics based on anti-cancer properties of the soybean protein Lunasin (from the Tagalog word "lunas" for cure. The technology can be used to identify potential drug targets and diagnostic biomarkers, and also as a research tool for...Read more about Narra Biosciences, LLC
Nexilico
Nexilico, Inc. is an early-stage startup with the mission to advance microbiome and precision medicine research and development by developing next generation of predictive, computational platforms that improve drug design and development as well as therapeutics clinical outcome...Read more about Nexilico
Nurix
Nurix is pioneering rational drug design in the emerging field of protein regulation by targeting E2 conjugating enzymes and E3 ligases that control the Ubiquitin Proteasome System (UPS).
Regulation of protein stability by the UPS is modulated by the activity of these E2...Read more about Nurix
Ogma Scientific
Ogma Scientific works with clients in the energy, mining and agriculture sectors and clients in the chemical industry to identify innovative treatment strategies for problems in industrial ecosystems. Our high-throughput screening services are uniquely
Omniox, Inc.
Omniox is an early stage biopharmaceutical company developing new medicines for hypoxic diseases. Hypoxia (oxygen deficiency) impacts cancer, cardiovascular diseases, trauma and many other conditions. The company has engineered an unusually stable oxygen carrier technology (H-...Read more about Omniox, Inc.
OncoRx Pharmaceuticals, Inc.
OncoRx Pharmaceuticals is an early-stage pharmaceutical company discovering and developing targeted therapies that control the progression of invasive malignant cancer. OncoRx has identified and tested drugs that markedly alter the sustained directional
OptoCeutics
Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.
Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy
Opus Biosciences
The mission of Opus Biosciences is to advance the field of lipid nanoparticle delivery through the development of safer, higher efficacy, cost effective, and exceedingly efficient LNPs, surpassing industry standards. Opus is committed to unlocking existing limitations within...Read more about Opus Biosciences
Photoswitch Biosciences Inc.
Photoswitch Biosciences was founded in 2010 to advance applications of designed-for-purpose, photo-activated ion channels. It became clear that new tools were needed to advance the research. The therapeutic mission has been separated so that Photoswitch Biosciences today can...Read more about Photoswitch Biosciences Inc.
Pow.Bio
Pow.Bio provides intelligent fermentation services for industrial and synthetic biology. The company's services combine continuous fermentation with advanced control methodology to quickly optimize the fermentation process and deliver high yields at low cost. The scale runs...Read more about Pow.Bio
Prolific Machines
Prolific Machines specializes in cell production with a unique manufacturing approach that combats climate change, enables space-food, and makes cell therapy accessible to everyone. The company's photomolecular biology platform leverages safe and effective tools — light,...Read more about Prolific Machines
Protiveris, Inc.
Protiveris Inc. develops and commercializes micro- and nanocantilever systems for academic research, drug discovery and development, bio-defense, protein research, and discovery of new pharmaceuticals and diagnostic applications.
Receptron, Inc.
Receptron, Inc. was founded to develop hormone receptor technology that modulates the endogenous thrombopoietin (TPO) receptor, a human hormone that stimulates patelet production.
Timeline 1987. Company founded InventorsAndrea Goldsmith, Robert...Read more about Receptron, Inc.
Redwood Bioscience Inc.
Redwood Bioscience, Inc. develops a protein-chemical engineering technology to produce antibody-drug conjugates and other semi-synthetic biotherapeutics. The company offers SMARTag site-specific protein modification and cytotoxin-linker technologies that enable the generation...Read more about Redwood Bioscience Inc.
Renovis, Inc.
Renovis, Inc. was a biopharmaceutical company developing drugs to treat neurological diseases and disorders.
Renovis, Inc. was acquired by Evotec AG in 2008.
InventorsReRx Therapeutics
ReRx is developing novel oral therapeutics to treat patients with severe metabolic diseases including obesity, metabolic syndrome, diabetes, and liver diseases. The company's therapeutics target metabolic pathways involved in regulating energy homeostasis and improve treatment...Read more about ReRx Therapeutics
Resvita Biosciences
Rewrite Therapeutics
Rewrite Therapeutics accelerates drug development using a proprietary CRISPR-based evolution platform. For more information, contact Shakked Halperin.
Formerly known as Evolve...Read more about Rewrite Therapeutics
RM2
Wound treatment.
Mary Phillips, Paul Mikus, and Boris RubinskyRead more about RM2
Scribe Therapeutics
Scribe is focused on the engineering, delivery, and development of next-generation CRISPR molecules to rewrite and repair the underlying cause of genetic disorders. The molecular engineering company was spun out of discoveries in the lab of UC Berkeley Professor of...Read more about Scribe Therapeutics
Singulex, Inc.
Singulex is an immunodiagnostics company at the forefront of Single Molecule Counting technology, a novel immunoassay technology recognized for unprecedented ultra sensitivity in the precision measurement of biomarkers. Singulex is the developer of the Singulex Clarity
...Read more about Singulex, Inc.Spotlight Therapeutics
Developer of next-generation gene editing therapeutics in a preclinical pipeline. The company creates programmable nucleases that selectively target and edit specific cell populations directly in the body. These engineered nucleases will enable direct intervention in vivo...Read more about Spotlight Therapeutics
Stylus Medicine
Stylus Medicine is on a mission to develop next-generation therapies for disease, based on the pioneering work of leaders in the fields of genome engineering and chromatin regulation.
suitX
suitX brought advanced accessible exoskeletons to industrial and medical markets with funding from venture capital, industry, and government.
Formerly known as U.S. Bionics.
Acquired by Ottobock in 2021.
Sunesis Pharmaceuticals Inc.
Sunesis is a biopharmaceutical company focused on the development and future commercialization of new oncology therapeutics for the treatment of hematologic and solid tumor cancers. Sunesis has built an experienced cancer drug development organization committed to improving the...Read more about Sunesis Pharmaceuticals Inc.
Synvivia, Inc.
Synvivia is a synthetic biology company that optimizes cell behavior for gene therapy manufacturing, providing a practical solution for genetically encoded biocontainment. The company is building genetically encoded biocontainment technologies that will enable the widespread...Read more about Synvivia, Inc.
Tenaya Therapeutics
Tenaya Therapeutics is shaping the future of heart disease treatment driven by a mission to discover, develop, and deliver curative therapies that address the underlying drivers of heart disease. Tenaya is developing therapies for rare genetic disorders as well as for more...Read more about Tenaya Therapeutics
Tessera Therapeutics, Inc.
Developer of gene writing technology designed to permanently make small and large alterations to the human genome. The company's technology helps scientists and clinicians with the ability to write small and large therapeutic messages into the genome to treat diseases at their...Read more about Tessera Therapeutics, Inc.
Thuris Corporation
Thuris Corporation was a biopharmaceutical company focused on medical device solutions to aid in drug development and diagnosis of central nervous system (CNS) disorders including mild cognitive impairment and Alzheimer's disease. Thuris was also developing pharmaceuticals for...Read more about Thuris Corporation
Tilden Bio
Development of photosynthetic bioproducts including natural plant essential oils, cannabinoids, and biopharmaceutical proteins. The technology has been applied to enhance yields of high-value photosynthetic bioproducts in the UC Berkeley Melis Laboratory.
Formerly known...Read more about Tilden Bio
Tularik Inc.
Tularik, Inc. engages in the discovery and development of orally available medicines that act through the regulation of gene expression. The company’s drugs include T67, T607, T131, T71, and T487. The T67 is an anti-cancer drug. The T607 would be used for treating gastric...Read more about Tularik Inc.
Valitor Inc.
Valitor, Inc. has developed novel methods of modifying therapeutic proteins to achieve substantial control over their pharmacokinetics, target specificity, and bioactivity. The company's technology platform can be broadly applied to improve the pharmacological properties of...Read more about Valitor Inc.
Vedere
Vedere Bio, Inc. was developing gene therapy products to restore functional vision to patients who have suffered vision loss from inherited retinal degenerations, as well as other causes of both genetic and non-genetic vision loss. Vedere aimed to restore lost vision regardless...Read more about Vedere
Vedere Bio II
Vedere Bio II is pioneering beyond traditional gene therapy to not just slow vision loss from inherited retinal degenerations (IRDs) or dry age-related macular degeneration (dry AMD) with geographic atrophy (GA), but actually restore it.
Vicinitas Therapeutics
Vicinitas Therapeutics is a biotechnology company focused on targeted protein stabilizers known as Deubiquituinase Targeting Chimeras (DUBTACs). The company’s mission is to use this proprietary technology to solve critical problems in human health by developing next-generation...Read more about Vicinitas Therapeutics
YourChoice Therapeutics
YourChoice Therapeutics is revolutionizing birth control options for women and men by developing hormone-free contraceptives and bringing them to market. Our technology is the result of a decade of research at the University of California, Berkeley and has been published in...Read more about YourChoice Therapeutics