Research Tools

Laguna Bio

Brief Description

Developer of drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company specializes in providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of a bispecific antibody drug, enabling patients to survive a deadly disease like cancer.

Timeline 2022. Company founded Inventors

Daniel Portnoy, Thomas Patrick Burke, Juliana Durack, Jonathan Lewis Portman, Christopher Rae, Rafael Jose Rivera Lugo, Kimberly Makiko Sogi, Sarah Ann Stanley,...

Kalinex, Inc.

Brief Description

Kalinex is developing technology that emulates the sense of smell, which is the only human/animal sense that has not yet been replicated in small devices and systems. The company's proprietary technology allows for the detection of molecules with extremely high sensitivity and selectivity. There is unaddressed need for such systems and a huge potential market in several industry verticals such as security (homeland defense), environmental monitoring, and petrochemicals.

Formerly known as Capil LLC.

Timeline 2004. Company founded Inventors

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Acrigen Biosciences, Inc.

Brief Description

Acrigin Biosciences is developing Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics. Acrigen’s proprietary technology leverages novel αCas and μCas CRISPR gene editors coupled with ErAcrs (engineered anti-CRISPR proteins) to create an editing toolbox with best-in-class efficiency and precision. The company's technology will expand the impact of CRISPR by improving the efficacy and safety of novel gene editing therapies.

Timeline 2019. Company founded Inventors

Jennifer Doudna, Christof Fellmann, Haridha...

Molecular Dynamics

Brief Description

The development of high speed, high throughput and highly accurate DNA sequencing methods was one prerequisite for the success of the Human Genome Project. In answer to this need, Richard Mathies and his lab at UC Berkeley developed a new method called capillary array electrophoresis (CAE) where multiple separations could be performed in parallel using bundles of microcapillaries and allowed the generation of over 2.8 million bases in 24 h.

Molecular Dynamics was acquired by Nycomed Amersham Pharmacia Biotech for approximately $256 million in 1998. Amersham was...

Rubicon Digital Mapping Associates

Brief Description

Rubicon Digital Mapping Associates was founded to commercialize tools that help users develop strong geologic field skills, based on technology developed in the lab of UC Berkeley Professor George Brimhall. GeoMapper and GeoLogger enable surface mapping, underground mapping, and drillhole logging using digital methods implemented in two integrated and compatible mapping software systems, one for mapping and the other for logging.

Timeline 2001. Company founded Inventors

George Brimhall, Erica Stanton, Abel Vanegas

Acacia Biosciences, Inc.

Brief Description

Acacia Biosciences, Inc. was a drug discovery technology company committed to the creation of proprietary assay systems and databases that facilitate the rapid development of biopharmaceutical s and agricultural chemicals. The Genome Reporter Matrix is the first in a series of novel tools that provide practical analysis of early stage chemicals by interpreting their effects across entire genomes. In addition to the GRM, Acacia's technology is used to discover novel targets and gene regulatory mechanisms.

Acacia Biosciences merged with Rosetta Inpharmatics in 1999...

A/F Protein Inc.

Brief Description

A/F Protein Inc. is the world's only commercial producer of antifreeze proteins purified from natural sources for sale to the research and development community. The company was spun out of discoveries in the lab of UC Berkeley Professor of Bioengineering and Mechanical Engineering Boris Rubinsky, an expert in the field of ice physics. Dr. Rubinsky reported on the ability of antifreeze proteins and glycoproteins to interact with mammalian cell membranes at hypothermic temperatures and protect such cells from depolarization and death. This important finding has led to...