Medical Therapeutics

Epigenetic Gene Editing

Brief Description

Epigenetic Gene Editing is a gene editing tools company dedicated to improvements in CRISPR-Cas9 editing by providing a fusion protein kit to gene editing companies.

Formerly known as EPI-CRISPRx.

Timeline 2021. Company founded Inventors

Enrique Lin Shiao, Jennifer Doudna

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Demetrix, Inc. works with nature to make rare ingredients readily accessible to promote healthier and happier lives. By using microorganisms such as baker's yeast and fermentation combined with the most advanced biotechnology, data science and automation, Demetrix can produce complex, sustainable ingredients at high purity and low cost. The company is initially focusing on producing cannabinoids to build its portfolio of ingredients. Exclusively licensed breakthrough technology from the University of California, Berkeley will soon enable Demetrix to commercially produce...

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Rewrite Therapeutics

Brief Description

Rewrite Therapeutics accelerates drug development using a proprietary CRISPR-based evolution platform. For more information, contact Shakked Halperin.

Formerly known as Evolve Biotech, and Rewrite Biotech.

The company was acquired by Intellia Therapeutics in 2022.

Timeline 2018. Company founded 2022. Acquired by Intellia Therapeutics Inventor

Shakked Halperin

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Genocea Biosciences, Inc.

Brief Description

Genocea finds targets of T cell responses to discover and develop life-changing medicines. The company created a pipeline of novel vaccine and immunotherapy programs that stimulate the T cell arm of the immune system, which is increasingly recognized as critical to generating protective immune responses against a wide array of diseases. Genocea designs its medicines using ATLASª, a proprietary technology platform. Genocea's platform has the potential to revolutionize vaccines and immunotherapies for a range of infectious diseases, cancers and autoimmune diseases. The...

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Photoswitch Biosciences Inc.

Brief Description

Photoswitch Biosciences was founded in 2010 to advance applications of designed-for-purpose, photo-activated ion channels. It became clear that new tools were needed to advance the research. The therapeutic mission has been separated so that Photoswitch Biosciences today can focus on providing advanced tools to the research community.

Our mission is to provide best-in-class instrumentation to the industrial and academic research communities. Founded by scientists familiar with need for reliable instrumentation and advanced software, the user experience is at the...

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iMEDD, Inc.

Brief Description

Drug delivery based on micro-engineering technology utilizing silicon microcapsules with nanofilters so that treatments can be controlled and targeted to particular cells and sites in the body.

The company licensed intellectual property that had been previously licensed to UC Berkeley spinout Iris Micromedical. The IP was developed in the lab of UC Berkeley Associate Professor of Engineering Mauro Ferrari, who moved to Ohio State University in 1999 as a professor of bioengineering, internal medicine, and mechanical engineering. In conjunction with Dr....

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DNA Sciences, Inc.

Brief Description

While gene sequencing and gene expression technologies have become relatively industrialized, genetic analysis is a time-consuming, labor intensive, and rate-limiting step in drug discovery. DNA Sciences, Inc. removed this bottleneck by developing a high-throughput system that miniaturizes and automates genotyping.

The company's genotyping technology relied on microchannel electrophoretic DNA separation technology combined with fluorescent detection of PCR-amplified DNA. The company licensed the technology from Amersham Pharmacia Biotech Ltd. (Uppsala, Sweden) and...

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Dahlia Biosciences

Brief Description Dahlia Biosciences is leading the development of cell-based RNA detection tools using CRISPR technology. The foundational RNA-targeting Cas9 technology was invented by Dr. Mitchell O’Connell and Dr. Sam Sternberg in the laboratory of Dr. Jennifer Doudna at UC Berkeley.

The company's vision is to empower scientists to study and isolate cells at high resolution via sensitive, robust, and multiplexed RNA detection in both fixed and live cells.

Timeline 2011. Company founded Inventors

Jennifer Doudna, Mitchell O'Connell, Benjamin Oakes,...