Medical Therapeutics

Genocea Biosciences, Inc.

Brief Description

Genocea finds targets of T cell responses to discover and develop life-changing medicines. The company created a pipeline of novel vaccine and immunotherapy programs that stimulate the T cell arm of the immune system, which is increasingly recognized as critical to generating protective immune responses against a wide array of diseases. Genocea designs its medicines using ATLASª, a proprietary technology platform. Genocea's platform has the potential to revolutionize vaccines and immunotherapies for a range of infectious diseases, cancers and autoimmune diseases. The...

Photoswitch Biosciences Inc.

Brief Description

Photoswitch Biosciences was founded in 2010 to advance applications of designed-for-purpose, photo-activated ion channels. It became clear that new tools were needed to advance the research. The therapeutic mission has been separated so that Photoswitch Biosciences today can focus on providing advanced tools to the research community.

Our mission is to provide best-in-class instrumentation to the industrial and academic research communities. Founded by scientists familiar with need for reliable instrumentation and advanced software, the user experience is at the...

Renovis, Inc.

Brief Description

Renovis, Inc. was a biopharmaceutical company developing drugs to treat neurological diseases and disorders.

Renovis, Inc. was acquired by Evotec AG in 2008.

Inventors David Lin, Percy Luu, John Ngai, Tito Serafini

Resvita Biosciences

Brief Description Resvita Biosciences seeks to restore and maintain the vitality of the skin by properly considering the skin microbiome as part of the human body. A harmless skin probiotic will continuously deliver the therapy that a body would to maintain skin health.

Through synthetic biology and metabolic engineering, the company's goal is to develop a safe and versatile skin microbial platform that can address the causes of skin aging and disease. Resvita Biosciences has a unique patented approach, a rich product pipeline, clear regulatory advantages, and an experienced...

iMEDD, Inc.

Brief Description

Drug delivery based on micro-engineering technology utilizing silicon microcapsules with nanofilters so that treatments can be controlled and targeted to particular cells and sites in the body.

The company licensed intellectual property that had been previously licensed to UC Berkeley spinout Iris Micromedical. The IP was developed in the lab of UC Berkeley Associate Professor of Engineering Mauro Ferrari, who moved to Ohio State University in 1999 as a professor of bioengineering, internal medicine, and mechanical engineering. In conjunction with Dr....

DNA Sciences, Inc.

Brief Description

While gene sequencing and gene expression technologies have become relatively industrialized, genetic analysis is a time-consuming, labor intensive, and rate-limiting step in drug discovery. DNA Sciences, Inc. removed this bottleneck by developing a high-throughput system that miniaturizes and automates genotyping.

The company's genotyping technology relied on microchannel electrophoretic DNA separation technology combined with fluorescent detection of PCR-amplified DNA. The company licensed the technology from Amersham Pharmacia Biotech Ltd. (Uppsala, Sweden) and...

Dahlia Biosciences

Brief Description Dahlia Biosciences is leading the development of cell-based RNA detection tools using CRISPR technology. The foundational RNA-targeting Cas9 technology was invented by Dr. Mitchell O’Connell and Dr. Sam Sternberg in the laboratory of Dr. Jennifer Doudna at UC Berkeley.

The company's vision is to empower scientists to study and isolate cells at high resolution via sensitive, robust, and multiplexed RNA detection in both fixed and live cells.

Timeline 2011. Company founded Inventors

Jennifer Doudna, Mitchell O'Connell, Benjamin Oakes,...

MRL Bio

Brief Description

The company is developing a unique drug delivery platform for tissue regeneration in acute and chronic wounds.

Timeline 2019. Company founded Inventors

Phillip Messersmith, Jing Cheng, Ellen Heber-Katz

Lymphax, Inc.

Brief Description

Lymphax, Inc. is a therapeutics company treating ocular diseases and conditions.

Formerly known as NewVision Bioscience, Inc.

Timeline 2019. Company founded Inventors

Lu Chen, Sammy Grimaldo, Meng Shi, Don Yuen

Laguna Bio

Brief Description

Developer of drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company specializes in providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of a bispecific antibody drug, enabling patients to survive a deadly disease like cancer.

Timeline 2022. Company founded Inventors

Daniel Portnoy, Thomas Patrick Burke, Juliana Durack, Jonathan Lewis Portman, Christopher Rae, Rafael Jose Rivera Lugo, Kimberly Makiko Sogi, Sarah Ann Stanley,...