Research Tools

Tilden Bio

Brief Description

Development of photosynthetic bioproducts including natural plant essential oils, cannabinoids, and biopharmaceutical proteins. The technology has been applied to enhance yields of high-value photosynthetic bioproducts in the UC Berkeley Melis Laboratory.

Formerly known as Tabletop Energy.

Timeline 2019. Company incorporated Inventors

Nico Betterle, Fiona Davies, Cinzia Formighieri, Diego Hidalgo Martinez, Henning Kirst, Andrew Saphire, Hsu Ching Wintz, Andreas Zurbriggen, Anastasios Melis

Tenaya Therapeutics

Brief Description

Tenaya Therapeutics is shaping the future of heart disease treatment driven by a mission to discover, develop, and deliver curative therapies that address the underlying drivers of heart disease. Tenaya is developing therapies for rare genetic disorders as well as for more prevalent heart conditions through three platforms: Gene Therapy, Cellular Regeneration, and Precision Medicine. The company was founded by leading cardiology researchers at the Gladstone Institutes and UT Southwestern, and backed by a top-tier syndicate of investors.

Timeline 2016...

Texas Fluorescence Labs

Brief Description

Texas Fluorescence Labs was a reagent and assay technologies company, spun out of modern fluorescent calcium indicator discoveries at UC Berkeley. The company specialized in pioneering new approaches to ion channel and ion transporter-focused basic and translational research and provided reagents, assays, and assay development services to scientists, universities, and laboratories worldwide for research in biochemistry, biomolecular screening, microbiology, and neuroscience.

In 2018, UC Berkeley Professor of Chemistry and Biochemistry Roger Tsien shared the Nobel...

Synvivia, Inc.

Brief Description

Synvivia is a synthetic biology company that optimizes cell behavior for gene therapy manufacturing, providing a practical solution for genetically encoded biocontainment. The company is building genetically encoded biocontainment technologies that will enable the widespread use of synthetic biology outside of the laboratory.

The company's technology was developed at UC Berkeley with grants from the NSF and DARPA. The work was published in ACS Synthetic Biology and featured as an Editor’s Choice in Science Magazine. Synvivia has exclusive license to the...

Artris Therapeutics, Inc.

Brief Description

Artris Therapeutics was founded to identify and develop cancer therapeutics. The company was co-founded by UC Berkeley Professor of Chemical Biology and Molecular Therapeutics Daniel Nomura.

Timeline

2017. Company founded Inventors

Leslie Bateman, Jessica Cestellos Spradlin, Tucker Huffman, David Miyamoto, Elizabeth Anne Moore, Truc Bang Nguyen, Daniel Nomura, James Arthur Olzmann, Allison Marie Roberts, Carl Ward

Ansa Biotechnologies

Brief Description

With synthetic DNA fueling innovation in biological research, therapeutics, diagnostics, and biomanufacturing, there is an urgent need for faster and more accurate DNA synthesis. Currently, DNA is manufactured via a chemical method that has remained essentially unchanged for 35 years and has approached a plateau. Ansa Biotechnologies is developing a faster, more accurate, and cleaner enzyme-based DNA synthesis technology. The technique promises to dramatically accelerate innovation in biological research and engineering.

The approach is based on polymerase-...

Shrink Technologies, Inc.

BRIEF DESCRIPTION

Shrink Technologies, Inc., based in Carlsbad, California, was acquired by Shrink Nanotechnologies, Inc. on May 29, 2009. Shrink Technologies specializes in developing innovative technologies, particularly focused on metal-enhanced fluorescence (MEF) applications. Their MEF technology, which integrates rapid prototyping methods with metal-fluorescence enhanced immunoassays, significantly enhances the sensitivity of diagnostic assays, making it possible to detect interactions that current methods miss. This technology has broad applications in drug discovery,...

OptoCeutics

Brief Description

Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.

Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy and digital biomarkers.

40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%. Optoceutics develops a masked 40 Hz...

IntegenX

Brief Description

IntegenX is the market leader of Rapid DNA technology for human identification in forensics and law enforcement applications. IntegenX’s RapidHIT technologies integrate advanced fluidics, optics, and biochemistry capabilities to produce sample-to-answer solutions for DNA-based human identity testing. The RapidHIT ID System for Crime Labs generates lab-...

Apertor Pharmaceuticals

Brief Description

Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational pipeline enabled by structure-guided design. The result is a first-in-class approach to solving important pharmacological problems and delivering new, high-value treatment options for patients. The company was co-founded by UC Berkeley Professor of Chemical & Biomolecular Engineering and of...