Research Tools

Apertor Pharmaceuticals

Brief Description

Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational pipeline enabled by structure-guided design. The result is a first-in-class approach to solving important pharmacological problems and delivering new, high-value treatment options for patients. The company was co-founded by UC Berkeley Professor of Chemical & Biomolecular Engineering and of...

Ansa Biotechnologies

Brief Description

With synthetic DNA fueling innovation in biological research, therapeutics, diagnostics, and biomanufacturing, there is an urgent need for faster and more accurate DNA synthesis. Currently, DNA is manufactured via a chemical method that has remained essentially unchanged for 35 years and has approached a plateau. Ansa Biotechnologies is developing a faster, more accurate, and cleaner enzyme-based DNA synthesis technology. The technique promises to dramatically accelerate innovation in biological research and engineering.

The approach is based on polymerase-...

Addition Therapeutics

Brief Description

Addition is transforming genetic medicine by developing RNA-only therapeutics that PRINT™ any genetic element at specific safe harbor sites.

Inventors

Kathy Collins, Jeremy John McIntyre, Sarah Madeline Palm, Heather Upton, Briana Nicole Van Treeck. Xiaozhu Zhang

Company Founders

Kathleen Collins

Timeline 2021. Company founded

Acrigen Biosciences, Inc.

Brief Description

Acrigin Biosciences is developing Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics. Acrigen’s proprietary technology leverages novel αCas and μCas CRISPR gene editors coupled with ErAcrs (engineered anti-CRISPR proteins) to create an editing toolbox with best-in-class efficiency and precision. The company's technology will expand the impact of CRISPR by improving the efficacy and safety of novel gene editing therapies.

Inventors

Jennifer Doudna, Christof Fellmann, Haridha Shivram, Kyle Watters

Company Founders

David...

A/F Protein Inc.

Brief Description

A/F Protein Inc. is the world's only commercial producer of antifreeze proteins purified from natural sources for sale to the research and development community. The company was spun out of discoveries in the lab of UC Berkeley Professor of Bioengineering and Mechanical Engineering Boris Rubinsky, an expert in the field of ice physics. Dr. Rubinsky reported on the ability of antifreeze proteins and glycoproteins to interact with mammalian cell membranes at hypothermic temperatures and protect such cells from depolarization and death. This important finding has led to...

Magnetic Tides

Brief Description

Magnetic Tides has developed a new non-invasive brain stimulation (NIBS) system capable of modulating brain function more reliably and effectively than previously existing NIBS methods.

NIBS is used as a research tool to safely, transiently alter the excitability state of targeted neurons when testing causal hypotheses about brain-behavior relationships. In addition, clinicians have recognized the potential of NIBS as a new intervention in the treatment of neurological and psychiatric disorders.

Timeline 2019. Company founded Inventors

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Ergodicity

Brief Description

Ergodicity develops analytical methods for the age of AI. The company takes a data-first approach to create next-generation optical tools that set new standards in the accessibility of information in chemical and biophysical analytics for biotech.

Inventors

Hendrik Utzat

Company Founders

UC Berkeley Assistant Professor of Chemistry Hendrik Utzat and Richard Maceiczyk

Timeline 2025. Company founded

Generation Lab

Brief Description

Generation Lab provides the first and only platform that measures the effectiveness of longevity interventions to identify what works. Co-founded by pre-eminent aging and longevity researcher Dr. Irina Conboy from UC Berkeley, Generation Lab combines an easy-to-use test with proprietary techniques to definitively measure molecular disbalance that indicates aging and risk of disease before symptoms arise. The company works with clinicians who can recommend personalized interventions to increase health, wellness, and longevity; and Generation Lab uniquely measures the...

Water Harvesting, Inc

Brief Description Water Harvesting Inc. was formed in 2018 to commercialize atmospheric water harvesting systems based on metal organic frameworks (MOFs) and address the global challenge of water scarcity. MOFs work for atmospheric water harvesting even under very arid conditions. Inventors

Farhad Fathieh, Nikita Hanikel, Markus Kalmutzki, Ievgen Kapustin, Hao Lyu, Mathieu Steven Prevot, Omar Yaghi, JingJing Yang, Bing Zhang

Company Founders

Frank Ramirez (Berkeley Law, JD, 1979), Chris Kay, Eugene Kapustin (UC Berkeley PhD, 2018, Chemistry), David Kuo (UC Berkeley, MS, 1985, Ph.D...

Algen Biotechnologies

Brief Description

Algen Biotechnologies is building a next-generation, functional genomics-based platform for the discovery of novel therapeutics for cancers with high unmet need. Algen’s research group focuses on developing and applying novel functional genomics technologies to address scientific challenges in drug discovery. The company's biologists and data scientists are collaborating to deliver innovative, patient-centric medicines for the toughest-to-treat diseases.

The company was founded to commercialize technology developed at UC Berkeley while Algen Biotechnologies CEO...