Research Tools

Pow.Bio

Brief Description

Pow.Bio provides intelligent fermentation services for industrial and synthetic biology. The company's services combine continuous fermentation with advanced control methodology to quickly optimize the fermentation process and deliver high yields at low cost. The scale runs from 1-100 liter capacity for bacteria, yeast, and filamentous fungi. The first-of-its-kind fermentation technology solves the capacity problem of bioproduction with high-performance continuous fermentation that can run for hundreds of hours. This holy grail of biology offers an order of magnitude step...

ZestBio

Brief Description A biotechnology company harnessing synthetic biology to convert the low value, abundant fruit and vegetable byproducts like citrus peels and sugar beet pulp into useful products such as household cleaning ingredients, bio-based plastics, vitamins, and other specialty chemicals, thereby enabling customers to receive renewable, eco-friendly products at a reasonable cost. Timeline 2017. Company founded. Inventors John Dueber, Ryan Joseph Protzko

Zephyrus Biosciences, Inc.

Brief Description

This life science research tools company was spun out of technology developed in the UC Berkeley bioengineering department. Zephyrus Biosciences developed medical research tools for single-cell analyses, enabling high resolution biology. The company's first product, called Milo, was a benchtop instrument that allowed researchers to search for specific proteins in about 1,000 single cells at once. This improved western blotting instrument made it possible to analyze individual cells for the first time. The high-throughput and high-selectivity protein fingerprinting gave...

Xenometrix, Inc.

Brief Description Xenometrix, Inc. developed proprietary gene response profiling and genotoxicity technologies to enable high throughput screening for genotoxicity, helping the pharmaceutical industry improve the effectiveness of drug discovery and development through lead compound optimization. The company's goal was to accelerate the selection of promising drug and chemical leads for pharmaceutical, chemical, and biotechnology industries. The company's bioinformatics team assembled a database of gene profiles for public domain pharmaceuticals. Timeline 1991. Company founded...

Water Harvesting, Inc

Brief Description Water Harvesting Inc. was formed in 2018 to commercialize atmospheric water harvesting systems based on metal organic frameworks (MOFs) and address the global challenge of water scarcity. MOFs work for atmospheric water harvesting even under very arid conditions. Timeline 2018. Company founded. Inventors Farhad Fathieh, Nikita Hanikel, Markus Kalmutzki, Ievgen Kapustin, Hao Lyu, Mathieu Steven Prevot, Omar Yaghi, JingJing Yang, Bing Zhang

Ogma Scientific

Brief Description

Ogma Scientific works with clients in the energy, mining and agriculture sectors and clients in the chemical industry to identify innovative treatment strategies for problems in industrial ecosystems. Our high-throughput screening services are uniquely tailored to identify successful treatments to stop undesirable microbial activity that impacts industrial processes. Examples include biosouring in the oil sector and acid mine drainage in the mining sector. Biosouring alone, caused by the inadvertent stimulation of microbial activity during oil or gas recovery, costs the...

Spiral Devices LLC

Brief Description

Spiral Devices LLC is a biotechnology company committed to developing and commercializing technologies that improve the in vivo delivery of biological molecules for studying and treating disease. The company's BioDriver particle bombardment device delivers biolactive molecules into cells.

The company was co-founded by Kenneth Greenberg, to commercialize technology he invented as a UC Berkeley postdoctoral fellow in MCB Neurobiology, where he developed gene therapies for neurological diseases using chemogenetics,...

Solidus Biosciences, Inc.

Brief Description

Solidus' mission for the pharmaceutical industry is to improve the process of new drug development by providing proprietary decision-enabling technology to enhance drug safety, efficiency, cost, and, thereby, productivity from investment in new drug research and development.

Formerly known as Solidus Networks. Inc.

Timeline 2005. Company founded. Inventors

Douglas Clark, Jonathan Dordick

Caribou Biosciences Inc.

Brief Description

Caribou Biosciences is a clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company’s genome-editing platform, including its Cas12a chRDNA technology, enables superior precision to develop cell therapies that are armored to potentially improve activity against diseases. Caribou is advancing a pipeline of off-the-shelf cell therapies from its CAR-T cell platform as readily available treatments for patients with hematologic malignancies and autoimmune diseases.

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Scribe Therapeutics

Brief Description

Scribe is focused on the engineering, delivery, and development of next-generation CRISPR molecules to rewrite and repair the underlying cause of genetic disorders. The molecular engineering company was spun out of discoveries in the lab of UC Berkeley Professor of Biochemistry, Biophysics and Structural Biology and Nobel Laureate Jennifer Doudna. Doudna co-founded Scribe with company CEO Benjamin Oakes, who received a PhD in Molecular and Cellular Biology from UC Berkeley in 2017, where he worked in the Doudna Lab and Savage Lab, UC Berkeley Associate Professor of...