Research Tools

Totality Biosciences

Brief Description

Totality Biosciences is producing plant-based human milk oligosaccharides (HMOs), a high-value bioactive found in human breast milk. The breast milk substitute promises to improve nutrition in infant formula. The company also intends to supply complex HMOs for research and development of therapeutics.

Inventors

Patrick Shih, Collin Robert E. Barnum

Company Founders

Patrick Shih

Timeline

2025. Company founded

Shrink Technologies, Inc.

Brief Description

Shrink Technologies, Inc., based in Carlsbad, California, was acquired by Shrink Nanotechnologies, Inc. on May 29, 2009. Shrink Technologies specializes in developing innovative technologies, particularly focused on metal-enhanced fluorescence (MEF) applications. Their MEF technology, which integrates rapid prototyping methods with metal-fluorescence enhanced immunoassays, significantly enhances the sensitivity of diagnostic assays, making it possible to detect interactions that current methods miss. This technology has broad applications in drug discovery,...

OptoCeutics

Brief Description

Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.

Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy and digital biomarkers.

40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%. Optoceutics develops a masked 40 Hz...

Ogma Scientific

Brief Description

Ogma Scientific works with clients in the energy, mining and agriculture sectors and clients in the chemical industry to identify innovative treatment strategies for problems in industrial ecosystems. Our high-throughput screening services are uniquely tailored to identify successful treatments to stop undesirable microbial activity that impacts industrial processes. Examples include biosouring in the oil sector and acid mine drainage in the mining sector. Biosouring alone, caused by the inadvertent stimulation of microbial activity during oil or gas recovery, costs the...

CryoVox Technologies

Brief Description

Crovox Technologies is developing new tools for the mass manufacturing of 3D cell cultures.

Inventors

Boris Rubinsky, Michal Adamkievicz, Ze'ev Shaked

Timeline 2024. Company founded

Spiral Devices LLC

Brief Description

Spiral Devices LLC is a biotechnology company committed to developing and commercializing technologies that improve the in vivo delivery of biological molecules for studying and treating disease. The company's BioDriver particle bombardment device delivers biolactive molecules into cells.

The company was co-founded by Kenneth Greenberg, to commercialize technology he invented as a UC Berkeley postdoctoral fellow in MCB Neurobiology, where he developed gene therapies for neurological diseases using chemogenetics,...

ZestBio

Brief Description A biotechnology company harnessing synthetic biology to convert the low value, abundant fruit and vegetable byproducts like citrus peels and sugar beet pulp into useful products such as household cleaning ingredients, bio-based plastics, vitamins, and other specialty chemicals, thereby enabling customers to receive renewable, eco-friendly products at a reasonable cost. Inventors

John Dueber, Ryan Joseph Protzko

Company Founders

John Dueber, Luke Latimer (UC Berkeley, Ph.D., Doctor of Philosophy, 2017, Chemistry), Ryan Protzko (UC Berkeley, Ph.D.,...

Zephyrus Biosciences, Inc.

Brief Description

This life science research tools company was spun out of technology developed in the UC Berkeley bioengineering department. Zephyrus Biosciences developed medical research tools for single-cell analyses, enabling high resolution biology. The company's first product, called Milo, was a benchtop instrument that allowed researchers to search for specific proteins in about 1,000 single cells at once. This improved western blotting instrument made it possible to analyze individual cells for the first time. The high-throughput and high-selectivity protein fingerprinting gave...

Xenometrix, Inc.

Brief Description Xenometrix, Inc. developed proprietary gene response profiling and genotoxicity technologies to enable high throughput screening for genotoxicity, helping the pharmaceutical industry improve the effectiveness of drug discovery and development through lead compound optimization. The company's goal was to accelerate the selection of promising drug and chemical leads for pharmaceutical, chemical, and biotechnology industries. The company's bioinformatics team assembled a database of gene profiles for public domain pharmaceuticals. Inventors Bruce Ames, Pauline Gee, Dorothy...

Vitrichoric, Inc.

Brief Description

Vitrichoric, Inc. develops technology for high-stability supercooling of aqueous solutions or suspensions for the preservation of biological matter.

Inventors

Gabriel Nastase, Boris Rubinsky, Gideon Ukpai

Timeline 2021. Company founded