Research Tools

Apertor Pharmaceuticals

Brief Description

Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational pipeline enabled by structure-guided design. The result is a first-in-class approach to solving important pharmacological problems and delivering new, high-value treatment options for patients. The company was co-founded by UC Berkeley Professor of Chemical & Biomolecular Engineering and of...

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Totality Biosciences

Brief Description

Totality Biosciences is producing plant-based human milk oligosaccharides (HMOs), a high-value bioactive found in human breast milk. The breast milk substitute promises to improve nutrition in infant formula. The company also intends to supply complex HMOs for research and development of therapeutics.

Timeline

2025. Company founded Inventors

Collin Robert E. Barnum, Patrick M. Shih

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OptoCeutics

Brief Description

Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.

Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy and digital biomarkers.

40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%. Optoceutics develops a masked 40 Hz...

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Ansa Biotechnologies

Brief Description

With synthetic DNA fueling innovation in biological research, therapeutics, diagnostics, and biomanufacturing, there is an urgent need for faster and more accurate DNA synthesis. Currently, DNA is manufactured via a chemical method that has remained essentially unchanged for 35 years and has approached a plateau. Ansa Biotechnologies is developing a faster, more accurate, and cleaner enzyme-based DNA synthesis technology. The technique promises to dramatically accelerate innovation in biological research and engineering.

The approach is based on polymerase-...

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Pow.Bio

Brief Description

Pow.Bio provides intelligent fermentation services for industrial and synthetic biology. The company has built an AI platform that rapidly identified better-performing process conditions, increasing output 2–3x from existing infrastructure within just 100 days. The company's services combine continuous fermentation with advanced control methodology to quickly optimize the fermentation process and deliver high yields at low cost. The scale runs from 1-100 liter capacity for bacteria, yeast, and filamentous fungi. The first-of-its-kind fermentation technology solves the...

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Generation Lab

Brief Description

Generation Lab provides the first and only platform that measures the effectiveness of longevity interventions to identify what works. Co-founded by pre-eminent aging and longevity researcher Dr. Irina Conboy from UC Berkeley, Generation Lab combines an easy-to-use test with proprietary techniques to definitively measure molecular disbalance that indicates aging and risk of disease before symptoms arise. The company works with clinicians who can recommend personalized interventions to increase health, wellness, and longevity; and Generation Lab uniquely measures the...

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Tenaya Therapeutics

Brief Description

Tenaya Therapeutics is shaping the future of heart disease treatment driven by a mission to discover, develop, and deliver curative therapies that address the underlying drivers of heart disease. Tenaya is developing therapies for rare genetic disorders as well as for more prevalent heart conditions through three platforms: Gene Therapy, Cellular Regeneration, and Precision Medicine. The company was spun out of a new method for creating three-dimensional human heart tissue from stem cells, developed in a collaboration between UC Berkeley Professor of Materials Science...

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RS3Dprints

Brief Description

3D printing for medical and food applications. Mass producing alternative steaks from alternative ground beef. Scalable solution for 3D printed alternative meat.

The Cryolithographic Technology was initially developed to produce biological organs for organ transplant. Realizing that there was an immediate commercial opportunity in food production, RS3Dprints was spun out of the lab.

Timeline 2016. Company founded Inventors

Boris Rubinsky, Ze'ev Shaked, Michal Adamkievicz