SBIR/STTR Recipient

EditPep, Inc.

Brief Description

CRISPR therapies enabled by a simple, potent delivery platform. The biotechnology company creates a class of peptides capable of delivering CRISPR enzymes into clinically-relevant and previously untransfectable cell types, enabling clients to get CRISPR therapies.

Inventors

Ross Wilson, Dana Foss, Alexander Marson, Srishti Sahu, David-Huy Nguyen, John Hunsinger, Daniel Carr

Company Founders

Dana Foss (UC Berkeley postdoc 2017-2022), UC Berkeley Assistant Adjunct Professor of Molecular Therapeutics Ross Wilson

Timeline 2021...

Xip Diagnostics

Brief Description

Xip Diagnostics develops analytical solutions that advance human and animal health at the point of need through in-house product development and industry-leading collaborations.

The company's disposable blood analyzers wirelessly upload lab-quality clinical measurements in minutes, providing blood testing with no hassles, no delays, and no instrument. These devices will be deployed in Emergency Departments (EDs), clinics, and eventually the home.

Xip Diagnostics Founder and CEO Dr. Octavian Florescu spun out the company to commercialize research discoveries...

Photoswitch Biosciences Inc.

Brief Description

Photoswitch Biosciences was founded in 2010 to advance applications of designed-for-purpose, photo-activated ion channels. It became clear that new tools were needed to advance the research. The therapeutic mission has been separated so that Photoswitch Biosciences today can focus on providing advanced tools to the research community.

Our mission is to provide best-in-class instrumentation to the industrial and academic research communities. Founded by scientists familiar with need for reliable instrumentation and advanced software, the user experience is at the...

mFluiDx

Brief Description

mFluiDx is aiming to develop the world’s lowest cost, automated point-of-care DNA diagnostic assay for small clinics. In small clinics, such as primary care out-patient clinics, disease diagnosis is typically done by observing symptoms or using paper-strip antibody tests. However, these methods have poor sensitivity compared to DNA diagnostics. Highly sensitive molecular DNA tests (PCR) are not often used because of cost and the need to send tests off-site resulting in a slow turnaround time (several days).

mFluiDx is a UC Berkeley startup developing Gates...

ReRx Therapeutics

Brief Description

ReRx is developing novel oral small molecule therapeutics to treat patients with severe metabolic diseases including obesity, metabolic syndrome, diabetes, and liver diseases. The company's therapeutics target metabolic pathways involved in regulating energy homeostasis and improve treatment outcomes compared to similar pharmacological agents.

Obesity and its associated metabolic diseases remain leading causes of preventable illness and mortality worldwide. Current front-line treatments, notably injectable incretin analogs that suppress appetite and reduce food...

Resvita Biosciences

Brief Description

Resvita Biosciences seeks to restore and maintain the vitality of the skin by properly considering the skin microbiome as part of the human body. A harmless skin probiotic will continuously deliver the therapy that a body would to maintain skin health.

Through synthetic biology and metabolic engineering, the company's goal is to develop a safe and versatile skin microbial platform that can address the causes of skin aging and disease. Resvita Biosciences has a unique patented approach, a rich product pipeline, clear regulatory advantages, and an experienced...

Calyx

Brief Description

Calyx is a materials science company that harnesses biology to provide low cost and highly accurate sensors for real-time detection and analysis of air chemicals in a variety of industries, including safety, healthcare, transportation, and food. The company offers commercial customers phage-based sensing and analysis of multiple gasses.

Company co-founders Ray Chiu and Benson Fan developed the company’s founding technology as a capstone project while they were students in the UC Berkeley-UCSF Masters in Bioengineering program. With the encouragement of UC Berkeley...

BreezeBio

Brief Description

BreezeBio develops innovative therapies through targeted delivery of genetic medicines. The company's founders share the vision that recent scientific advancements in engineering CRISPR components and delivery vehicles offer a groundbreaking opportunity to develop safe and effective medicines for genetic diseases.

The company's proprietary Polymer nanoparticle can deliver CRISPR protein and gRNA. CRISPR in a protein form has many advantages, delivery has been a challenge limiting its application. To deliver CRISPR protein, encapsulation of CRISPR ribonucleoprotein...

ZestBio

Brief Description A biotechnology company harnessing synthetic biology to convert the low value, abundant fruit and vegetable byproducts like citrus peels and sugar beet pulp into useful products such as household cleaning ingredients, bio-based plastics, vitamins, and other specialty chemicals, thereby enabling customers to receive renewable, eco-friendly products at a reasonable cost. Inventors

John Dueber, Ryan Joseph Protzko

Company Founders

John Dueber, Luke Latimer (UC Berkeley, Ph.D., Doctor of Philosophy, 2017, Chemistry), Ryan Protzko (UC Berkeley, Ph.D.,...

YourChoice Therapeutics

Brief Description

YourChoice Therapeutics is revolutionizing birth control options for women and men by developing hormone-free contraceptives and bringing them to market. Our technology is the result of a decade of research at the University of California, Berkeley and has been published in numerous high-impact journals.

Inventors

Yuriy Kirichok, Polina Lishko, Nadja Mannowetz, Melissa Miller

Company Founders

Nadja Mannowetz, Akash Bakshi

Timeline 2018. Company founded