Medical Therapeutics

CalGen Therapeutics

Brief Description

Developer of a therapeutic inhaled antisense technology designed to prevent and treat respiratory infections.

Timeline 2021. Company founded Inventors

Kasper Karstensen, Sakari Kauppinen, Anders Michael Naar, Chi Zhu

Biotock

Brief Description

Development of treatments for age-related macular degeneration, a leading cause of blindness.

Timeline 2022. Company founded Inventors

Monika Maria Haoui, Polina Lishko

AsparaGlue

Brief Description

AsparaGlue has developed a superglue-like medical adhesive for external wound closure and internal tissue adhesion. The proprietary technology is the world’s only biocompatible and biodegradable medical superglue.

Timeline 2023. Company founded; joined Berkeley Skydeck accelerator, cohort 16 Inventors

Philip Messersmith, Subhajit Pal, Ji Soo Shin, Kelsey Gray DeFrates

Apertor Pharmaceuticals

Brief Description

Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational pipeline enabled by structure-guided design. The result is a first-in-class approach to solving important pharmacological problems and delivering new, high-value treatment options for patients. The company was co-founded by UC Berkeley Professor of Chemical & Biomolecular Engineering and of...

Chiron Corporation

Brief Description

Chiron Corporation was an American biotechnology company engaged in biopharmaceuticals, vaccines and blood testing.

Timeline 1981. Company founded 1990. Company Initial Public Offering on NASDAQ under the ticker symbol of CHIR. 2006. Acquired by Novartis Inventors

Henry Chang, Felix Karim, Gerald Rubin, Marc Therrien, David Wassarman

Cell-X

Brief Description

Editing T-cells with nanopore-electroporation to improve CRISPR-Cas9 editing capabilities.

Timeline 2021. Company founded Inventors

YuHong Cao, Jennifer Doudna, Enbo Ma, Peidong Yang

4D Molecular Therapeutics LLC

Brief Description 4D Molecular Therapeutics is a global leader in gene therapy product research & development using scientific innovation to unlock the full potential of gene therapy for patients with genetic diseases. Their robust discovery platform, termed Directed Vector Evolution, empowers us to create customized gene delivery vehicles (novel AAV vectors) to deliver genes to any tissue or organ in the body. These customized products allow us to deliver normal genes to tissues with defective genes (as occurs in genetic diseases). This 4DMT discovery technology was originally developed...

Epigenetic Gene Editing

Brief Description

Epigenetic Gene Editing is a gene editing tools company dedicated to improvements in CRISPR-Cas9 editing by providing a fusion protein kit to gene editing companies.

Formerly known as EPI-CRISPRx.

Timeline 2021. Company founded Inventors

Enrique Lin Shiao, Jennifer Doudna

Demetrix, Inc.

Brief Description

Demetrix, Inc. works with nature to make rare ingredients readily accessible to promote healthier and happier lives. By using microorganisms such as baker's yeast and fermentation combined with the most advanced biotechnology, data science and automation, Demetrix can produce complex, sustainable ingredients at high purity and low cost. The company is initially focusing on producing cannabinoids to build its portfolio of ingredients. Exclusively licensed breakthrough technology from the University of California, Berkeley will soon enable Demetrix to commercially produce...

Rewrite Therapeutics

Brief Description

Rewrite Therapeutics accelerates drug development using a proprietary CRISPR-based evolution platform. For more information, contact Shakked Halperin.

Formerly known as Evolve Biotech, and Rewrite Biotech.

The company was acquired by Intellia Therapeutics in 2022.

Timeline 2018. Company founded 2022. Acquired by Intellia Therapeutics Inventor

Shakked Halperin