Medical Therapeutics

ReRx Therapeutics

Brief Description

ReRx is developing novel oral therapeutics to treat patients with severe metabolic diseases including obesity, metabolic syndrome, diabetes, and liver diseases. The company's therapeutics target metabolic pathways involved in regulating energy homeostasis and improve treatment outcomes compared to similar pharmacological agents.

Timeline 2023. Company founded Inventors

Chi Zhu, Anders Michael Naar, Justin Yu-Sun Lee

GenoptX, LLC

Brief Description

A CRISPR-based gene editing company.

Formerly known as Syncodi.

Timeline 2019. Company founded. Inventors

Jennifer Doudna, Abraham Isser Flamholz, Dana Nadler, Benjamin Oakes, David Frank Savage

Geneditor Biosciences, Inc.

Brief Description

Geneditor Biosciences is a pre-clinical stage gene editing company focused on the treatment of rare cancers with unmet medical needs.

Timeline 2021. Company founded. Inventor

Jennifer Doudna

Evercrisp Biosciences

Brief Description

Evercrisp Biosciences is a biotechnology company engineering self-deliverable CRISPR genome editors intended to improve the area of oncology. The company focuses on the discovery and development of protein-based genome editors as therapeutics for multiple disease areas, enabling healthcare organizations to have novel enzymes with high cell permeability and editing efficiency.

Timeline 2021. Company founded. Inventor

Jennifer Doudna

EditPep, Inc.

Brief Description

CRISPR therapies enabled by a simple, potent delivery platform. The biotechnology company creates a class of peptides capable of delivering CRISPR enzymes into clinically-relevant and previously untransfectable cell types, enabling clients to get CRISPR therapies.

Timeline 2021. Company founded. 2023. Company participated Berkeley SkyDeck accelerator, Batch 16. Inventor

Ross Wilson, Dana Foss, Alexander Marson, Srishti Sahu, David-Huy Nguyen, John Hunsinger, Daniel Carr

Tessera Therapeutics, Inc.

Brief Description

Developer of gene writing technology designed to permanently make small and large alterations to the human genome. The company's technology helps scientists and clinicians with the ability to write small and large therapeutic messages into the genome to treat diseases at their source, enabling healthcare providers to cure their patients and improve their lives.

Tessera Scientific Advisory Board Member David Schaffer co-invented the company's foundational technology as UC Berkeley Professor of Chemical and Biomolecular Engineering, Bioengineering, Molecular and Cell...

Azalea Therapeutics, Inc.

Brief Description

Azalea Therapeutics is an early-stage biotech startup on a mission to revolutionize genomic medicines. By designing vehicles that enable cell-specific delivery inside the body, the company aims to unlock precision therapeutics for genetic diseases and unleash the promise of cellular-based therapies. The company's co-founders include Jennifer Doudna, a Nobel Laureate in Chemistry and UC Berkeley Professor of Biochemistry, Biophysics and Structural Biology, with Postdocs and a PhD student from her lab: CEO/CSO Jennifer Hamilton (PhD, 2018-2023); Founding Scientist Connor...

Pow.Bio

Brief Description

Pow.Bio provides intelligent fermentation services for industrial and synthetic biology. The company's services combine continuous fermentation with advanced control methodology to quickly optimize the fermentation process and deliver high yields at low cost. The scale runs from 1-100 liter capacity for bacteria, yeast, and filamentous fungi. The first-of-its-kind fermentation technology solves the capacity problem of bioproduction with high-performance continuous fermentation that can run for hundreds of hours. This holy grail of biology offers an order of magnitude step...

Frontier Medicines Corporation

Brief Description

Frontier Medicines was founded to develop medical treatments for currently "undruggable" diseases. The clinical stage precision medicine company pioneers medicines for genetically-defined patient populations in oncology and immunology, and plans to broaden its therapeutic focus over time. The company uses chemoproteomics - an innovative approach to chemically interrogate proteins in living systems – to discover and pharmacologically target new binding pockets (or "hotspots") on proteins, making them accessible to small-molecule drug discovery and development. The...

YourChoice Therapeutics

Brief Description

YourChoice Therapeutics is revolutionizing birth control options for women and men by developing hormone-free contraceptives and bringing them to market. Our technology is the result of a decade of research at the University of California, Berkeley and has been published in numerous high-impact journals.

Timeline 2018. Company founded Inventors

Yuriy Kirichok, Polina Lishko, Nadja Mannowetz, Melissa Miller