Medical Therapeutics

EnVoy-LAB

Brief Description

EnVoy-LAB is advancing next-generation production of life-saving medical radioisotopes for contract development and manufacturing organizations (CDMOs), radiopharmacies, pharmaceutical companies, and healthcare systems.

The company is developing novel cyclotron-based methods for producing Actinium-225 and Lead-212, two of the most promising isotopes for targeted alpha therapy. EnVoy-LAB's technologies enable decentralized, scalable, and high-purity isotope production using existing standard cyclotrons, increasing supply for transformative cancer treatments....

EditPep, Inc.

Brief Description

CRISPR therapies enabled by a simple, potent delivery platform. The biotechnology company creates a class of peptides capable of delivering CRISPR enzymes into clinically-relevant and previously untransfectable cell types, enabling clients to get CRISPR therapies.

Inventors

Ross Wilson, Dana Foss, Alexander Marson, Srishti Sahu, David-Huy Nguyen, John Hunsinger, Daniel Carr

Company Founders

Dana Foss (UC Berkeley postdoc 2017-2022), UC Berkeley Assistant Adjunct Professor of Molecular Therapeutics Ross Wilson

Timeline 2021...

Totality Biosciences

Brief Description

Totality Biosciences is producing plant-based human milk oligosaccharides (HMOs), a high-value bioactive found in human breast milk. The breast milk substitute promises to improve nutrition in infant formula. The company also intends to supply complex HMOs for research and development of therapeutics.

Inventors

Patrick Shih, Collin Robert E. Barnum

Company Founders

Patrick Shih

Timeline

2025. Company founded

Sift Biosciences

Brief Description

Sift Biosciences supercharges existing cancer therapies by leveraging artificial intelligence and high-throughput cellular screening to discover and design immunotherapy boosters that significantly extend cancer patient survival. The company was co-founded by Yue Clare Lou (BS ’18 Microbial Biology; PhD ’23 Microbiology) and Maddie Williams (PhD student '23-present, Molecular & Cell Biology) to commercize technology developed during their doctoral research at UC Berkeley.

Inventors

Yue "Clare" Lou, Madeline Dee Williams

Company Founders

Yue "Clare" Lou (...

Redwood Bioscience Inc.

Brief Description

Redwood Bioscience, Inc. develops a protein-chemical engineering technology to produce antibody-drug conjugates and other semi-synthetic biotherapeutics. The company offers SMARTag site-specific protein modification and cytotoxin-linker technologies that enable the generation of homogenous bioconjugates engineered to enhance potency, safety, and stability. Its SMARTag platform provides precise payload positioning and defined stoichiometry of payload-protein ratios. The company was incorporated in 2008 and is based in Emeryville, California. Redwood Bioscience, Inc....

Photoswitch Biosciences Inc.

Brief Description

Photoswitch Biosciences was founded in 2010 to advance applications of designed-for-purpose, photo-activated ion channels. It became clear that new tools were needed to advance the research. The therapeutic mission has been separated so that Photoswitch Biosciences today can focus on providing advanced tools to the research community.

Our mission is to provide best-in-class instrumentation to the industrial and academic research communities. Founded by scientists familiar with need for reliable instrumentation and advanced software, the user experience is at the...

OptoCeutics

Brief Description

Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.

Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy and digital biomarkers.

40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%. Optoceutics develops a masked 40 Hz...

Ogma Scientific

Brief Description

Ogma Scientific works with clients in the energy, mining and agriculture sectors and clients in the chemical industry to identify innovative treatment strategies for problems in industrial ecosystems. Our high-throughput screening services are uniquely tailored to identify successful treatments to stop undesirable microbial activity that impacts industrial processes. Examples include biosouring in the oil sector and acid mine drainage in the mining sector. Biosouring alone, caused by the inadvertent stimulation of microbial activity during oil or gas recovery, costs the...

Moment Bio

Brief Description

Developing curative therapies through versatile RNA targeting

Inventors

Patrick David Hsu

Timeline 2022. Company founded

Zenith Therapeutics

Brief Description

Zenith Therapeutics is redefining drug discovery through a new approach to protein degradation, making hard-to-drug targets of high therapeutic value accessible to drug discovery.

Inventors

Julia Sabine Schaletzky, Michael Rape, Edward Eric Wehri, Andrew G. Manford, Srivdya Chandrasekhar, Daniel K. Nomura, Nathaniel J. Henning

Timeline 2022. Company founded