Medical Therapeutics

Totality Biosciences

Brief Description

Totality Biosciences is producing plant-based human milk oligosaccharides (HMOs), a high-value bioactive found in human breast milk. The breast milk substitute promises to improve nutrition in infant formula. The company also intends to supply complex HMOs for research and development of therapeutics.

Inventors

Patrick Shih, Collin Robert E. Barnum

Company Founders

Patrick Shih

Timeline

2025. Company founded

Sift Biosciences

Brief Description

Sift Biosciences supercharges existing cancer therapies by leveraging artificial intelligence and high-throughput cellular screening to discover and design immunotherapy boosters that significantly extend cancer patient survival. The company was co-founded by Yue Clare Lou (BS ’18 Microbial Biology; PhD ’23 Microbiology) and Maddie Williams (PhD student '23-present, Molecular & Cell Biology) to commercize technology developed during their doctoral research at UC Berkeley.

Inventors

Yue "Clare" Lou, Madeline Dee Williams

Company Founders

Yue "Clare" Lou (...

Redwood Bioscience Inc.

Brief Description

Redwood Bioscience, Inc. develops a protein-chemical engineering technology to produce antibody-drug conjugates and other semi-synthetic biotherapeutics. The company offers SMARTag site-specific protein modification and cytotoxin-linker technologies that enable the generation of homogenous bioconjugates engineered to enhance potency, safety, and stability. Its SMARTag platform provides precise payload positioning and defined stoichiometry of payload-protein ratios. The company was incorporated in 2008 and is based in Emeryville, California. Redwood Bioscience, Inc....

Photoswitch Biosciences Inc.

Brief Description

Photoswitch Biosciences was founded in 2010 to advance applications of designed-for-purpose, photo-activated ion channels. It became clear that new tools were needed to advance the research. The therapeutic mission has been separated so that Photoswitch Biosciences today can focus on providing advanced tools to the research community.

Our mission is to provide best-in-class instrumentation to the industrial and academic research communities. Founded by scientists familiar with need for reliable instrumentation and advanced software, the user experience is at the...

OptoCeutics

Brief Description

Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.

Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy and digital biomarkers.

40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%. Optoceutics develops a masked 40 Hz...

Ogma Scientific

Brief Description

Ogma Scientific works with clients in the energy, mining and agriculture sectors and clients in the chemical industry to identify innovative treatment strategies for problems in industrial ecosystems. Our high-throughput screening services are uniquely tailored to identify successful treatments to stop undesirable microbial activity that impacts industrial processes. Examples include biosouring in the oil sector and acid mine drainage in the mining sector. Biosouring alone, caused by the inadvertent stimulation of microbial activity during oil or gas recovery, costs the...

Moment Bio

Brief Description

Developing curative therapies through versatile RNA targeting

Inventors

Patrick David Hsu

Timeline 2022. Company founded

Zenith Therapeutics

Brief Description

Zenith Therapeutics is redefining drug discovery through a new approach to protein degradation, making hard-to-drug targets of high therapeutic value accessible to drug discovery.

Inventors

Julia Sabine Schaletzky, Michael Rape, Edward Eric Wehri, Andrew G. Manford, Srivdya Chandrasekhar, Daniel K. Nomura, Nathaniel J. Henning

Timeline 2022. Company founded

CryoVox Technologies

Brief Description

Crovox Technologies is developing new tools for the mass manufacturing of 3D cell cultures.

Inventors

Boris Rubinsky, Michal Adamkievicz, Ze'ev Shaked

Timeline 2024. Company founded

QSX Bio

Brief Description

Developing medical therapeutics and vaccines through biosynthesis of natural compounds in plants.

Inventors

Jay Keasling, Yuzhong Liu, Henrik Scheller, Xiaoyue Chen, Samantha Aiko Crowe, James Reed, Laetitia Martin, Graham Arthur Hudson, Fei Gan

Company Founders

Yuzhong Liu

Timeline 2025. Company founded