IPIRA Startups

IPIRA Startups

Stylus Medicine

Brief Description

Stylus Medicine is on a mission to develop next-generation therapies for disease, based on the pioneering work of leaders in the fields of genome engineering and chromatin regulation.

Timeline 2022. Company founded. Inventor

Patrick David Hsu

Spotlight Therapeutics

Brief Description

Developer of next-generation gene editing therapeutics in a preclinical pipeline. The company creates programmable nucleases that selectively target and edit specific cell populations directly in the body. These engineered nucleases will enable direct intervention in vivo like a true administered biologic. Spotlight Therapeutics co-founders include Dr. Patrick Hsu, a UC Berkeley Assistant Professor of Bioengineering and co-founder of the Arc Institute.

Timeline 2017. Company founded. Inventors

Colleen McGourty, Lorena de Onate, Ross...

Spiral Devices LLC

Brief Description

Spiral Devices LLC is a biotechnology company committed to developing and commercializing technologies that improve the in vivo delivery of biological molecules for studying and treating disease. The company's BioDriver particle bombardment device delivers biolactive molecules into cells.

The company was co-founded by Kenneth Greenberg, to commercialize technology he invented as a UC Berkeley postdoctoral fellow in MCB Neurobiology, where he developed gene therapies for neurological diseases using chemogenetics,...

Solidus Biosciences, Inc.

Brief Description

Solidus' mission for the pharmaceutical industry is to improve the process of new drug development by providing proprietary decision-enabling technology to enhance drug safety, efficiency, cost, and, thereby, productivity from investment in new drug research and development.

Formerly known as Solidus Networks. Inc.

Timeline 2005. Company founded. Inventors

Douglas Clark, Jonathan Dordick

Sonera Magnetics

Brief Description

Magnetometers are nearly ubiquitous in today’s world, fueling applications as diverse as medical diagnostics and self-driving cars. The most sensitive magnetometers, however, can only operate at extreme temperatures and in a shielded environment that isolates the sensor from ambient magnetic fields. Sonera Magnetics is developing a magnetometer that can operate at room temperature and in portable form factors with sensitivity comparable to the best magnetic sensors available today, dramatically increasing potential applications.

Co-founders Dominic Labanowski and...

SMART Pad LLC

Brief Description

SMART Pad is commercializing a completely redesigned Chemical Mechanical Planarization (CMP) pad for the semiconductor industry. CMP processes have not changed much since their introduction by IBM in 1983, consisting of polyurethane polishing pads, polishing slurries with abrasive particles and pad conditioners for pad resurfacing.

SMART Pad co-founder Sunghoon Lee developed the company's foundational technology while earning his PhD in the lab of UC Berkeley Professor of Mechanical Engineering David Dornfeld.

Timeline 2018...

Caribou Biosciences Inc.

Brief Description

Caribou Biosciences is a clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company’s genome-editing platform, including its Cas12a chRDNA technology, enables superior precision to develop cell therapies that are armored to potentially improve activity against diseases. Caribou is advancing a pipeline of off-the-shelf cell therapies from its CAR-T cell platform as readily available treatments for patients with hematologic malignancies and autoimmune diseases.

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Scribe Therapeutics

Brief Description

Scribe is focused on the engineering, delivery, and development of next-generation CRISPR molecules to rewrite and repair the underlying cause of genetic disorders. The molecular engineering company was spun out of discoveries in the lab of UC Berkeley Professor of Biochemistry, Biophysics and Structural Biology and Nobel Laureate Jennifer Doudna. Doudna co-founded Scribe with company CEO Benjamin Oakes, who received a PhD in Molecular and Cellular Biology from UC Berkeley in 2017, where he worked in the Doudna Lab and Savage Lab, UC Berkeley Associate Professor of...

Neomorphic Software

Brief Description

Neomorphic uses proprietary software algorithms and computing infrastructure to analyze, assemble and annotate genomic and expressed gene sequence data. Neomorphic's bioinformatics capabilities have been demonstrated in several scientific settings, including the Drosophila annotation jamboree sponsored by Celera Genomics, and the Genome Annotation Assessment Project. Through these efforts, Neomorphic demonstrated that its tools are the most accurate at identifying genes and other regulatory regions within genomic sequence. Neomorphic's work with its collaborators on...

Cortera Neurotechnologies

Brief Description

Cortera Neurotechnologies, Inc. designs medical devices aimed at revolutionizing the treatment of incurable neurological conditions. The company's mission was to deliver innovative products that improve patient care, quality of life and advance neuroscientific research.

Rikky Muller (PhD ’13 EECS) invented the company's foundational technology, a micro-electrocorticography (ECoG) device, as a PhD student in electrical engineering and computer sciences at UC Berkeley. The small implant — as thin as plastic wrap and as flexible as a soft contact lens — can record...