IPIRA Startups

IPIRA Startups

Apertor Pharmaceuticals

Brief Description

Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational pipeline enabled by structure-guided design. The result is a first-in-class approach to solving important pharmacological problems and delivering new, high-value treatment options for patients. The company was co-founded by UC Berkeley Professor of Chemical & Biomolecular Engineering and of...

Evergreen Saponins

Brief Description

Evergreen Saponins is commercializing a sustainable, scalable production method for saponins, unlocking a new supply chain for an essential ingredient in processed food, bio-pesticides, medicines, vaccines, and more. Early in his career, company founder Dr. Ricardo San Martin developed techniques for harvesting saponins from the wood and bark of mature wild trees in Chile, fueling demand for the additive worldwide. Now the chemical engineer has invented a breakthrough method to extract commercial-grade saponins from the leaves of Chilean soapbark trees, Quillaja...

Totality Biosciences

Brief Description

Totality Biosciences is producing plant-based human milk oligosaccharides (HMOs), a high-value bioactive found in human breast milk. The breast milk substitute promises to improve nutrition in infant formula. The company also intends to supply complex HMOs for research and development of therapeutics.

Timeline

2025. Company founded Inventors

Collin Robert E. Barnum, Patrick M. Shih

OptoCeutics

Brief Description

Advancing non-invasive light technologies to stimulate the brain and improve cognitive function.

Through clinical trials, Optoceutics tests and develop solutions to treat and diagnose neurodegenerative diseases using emerging gamma stimulation therapy and digital biomarkers.

40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%. Optoceutics develops a masked 40 Hz...

HypO2Regen Therapeutics

Brief Description

HypO2Regen’s is developing novel, disease-modifying therapeutics for chronic intractable inflammatory diseases, including what would be the first cell-free stem cell treatment that induces true regeneration of tissue damaged by chronic inflammation. The company's first focus on improving the lives of more than 300 million people in the United States and Europe with moderate to severe periodontitis, up to 70% of whom are either undertreated or untreated.

Timeline 2024. Company founded Inventors

Phillip Messersmith, Jing Cheng, Ellen Heber-Katz

FLX Micro, Inc.

Brief Description

FLX Micro, Inc. manufactures silicon carbide-based microsensors. The company develops its products through silicon carbide deposition and microfabrication technology platform. Its products are used in various applications, such as automotive, energy, environmental, and manufacturing. The company was formerly known as Fiberlead, Inc.

Timeline 2000. Company founded. Inventors

Di Gao, Roger Howe, Roya Maboudian

Imprint Energy, Inc.

Brief Description

Imprint Energy aims to reshape the battery landscape. Currently available battery technologies limit the pace of improvement in design and functionality of portable electronic devices. Imprint Energy will address these shortcomings with its breakthrough zinc-based rechargeable battery technology, ZincPolyª. ZincPolyª battery technology removes longstanding limitations on the rechargeability of zinc-based batteries and enables the production of ultrathin, flexible, high energy density rechargeable batteries for significantly lower cost and without the design limitations or...

Abacus Power, Inc.

Brief Description

Abacus Power is pioneering power delivery systems that increase power density and efficiency for data centers, satellites, and the aerospace industry.

Timeline 2024. Company founded Inventors

Robert Pilawa-Podgurski, Yicheng Zhu, Nathan Ellis

TeraOps

Brief Description

Developer of OmniScope, a compact, portable night vision goggle system with multi-spectral sensing and enhanced color visualization.

Timeline 1996. Company founded Inventors

Leon O. Chua, Tamas Roska, Frank Werblin, Lin Yang

Vivere Oncotherapies

Brief Description

Gene and cell therapies for cancer.

Timeline 2024. Company founded. Inventors

Adam Schieferecke, John Dueber, David Schaffer, Juan Eduardo Hurtado, Hyun-Cheol Lee