IPIRA Startups

IPIRA Startups

Noble Thermodynamic Systems

Brief Description

Noble Thermodynamics is a clean-tech startup spun out from the Combustion Analysis Laboratories at University of California, Berkeley. Our core technology, the Argon Power Cycle, is a closed-loop IC engine cycle using a noble gas working fluid to increase efficiency and facilitate exhaust product separation. We are focused on applications in carbon-free power production, deep grid-energy storage, enhanced oil recovery, and carbon capture and sequestration.

Inventors

Jyh-Yuan Chen, Robert Dibble, Timothy Burke Sennott, Miguel Sierra Aznar

Company Founders

UC...

CaseForge, Inc.

Brief Description

CaseForge produces personalized stabilizers for use in research and clinical imaging. These stabilizers interface with medical devices to precisely position the patient and eliminate motion, guaranteeing comfortable, fast, simple placement consistency across treatments.

The company was founded by graduate students in the lab of Dr. Jack Gallant, a professor in the UC Berkeley Department of Psychology, and an affiliate in Electrical Engineering and Computer Science, and programs in Neuroscience, Bioengineering, Biophysics and Vision...

Zephyrus Biosciences, Inc.

Brief Description

This life science research tools company was spun out of technology developed in the UC Berkeley bioengineering department. Zephyrus Biosciences developed medical research tools for single-cell analyses, enabling high resolution biology. The company's first product, called Milo, was a benchtop instrument that allowed researchers to search for specific proteins in about 1,000 single cells at once. This improved western blotting instrument made it possible to analyze individual cells for the first time. The high-throughput and high-selectivity protein fingerprinting gave...

EnVoy-LAB

Brief Description

EnVoy-LAB is advancing next-generation production of life-saving medical radioisotopes for contract development and manufacturing organizations (CDMOs), radiopharmacies, pharmaceutical companies, and healthcare systems.

The company is developing novel cyclotron-based methods for producing Actinium-225 and Lead-212, two of the most promising isotopes for targeted alpha therapy. EnVoy-LAB's technologies enable decentralized, scalable, and high-purity isotope production using existing standard cyclotrons, increasing supply for transformative cancer treatments....

EditPep, Inc.

Brief Description

CRISPR therapies enabled by a simple, potent delivery platform. The biotechnology company creates a class of peptides capable of delivering CRISPR enzymes into clinically-relevant and previously untransfectable cell types, enabling clients to get CRISPR therapies.

Inventors

Ross Wilson, Dana Foss, Alexander Marson, Srishti Sahu, David-Huy Nguyen, John Hunsinger, Daniel Carr

Company Founders

Dana Foss (UC Berkeley postdoc 2017-2022), UC Berkeley Assistant Adjunct Professor of Molecular Therapeutics Ross Wilson

Timeline 2021...

Xip Diagnostics

Brief Description

Xip Diagnostics develops analytical solutions that advance human and animal health at the point of need through in-house product development and industry-leading collaborations.

The company's disposable blood analyzers wirelessly upload lab-quality clinical measurements in minutes, providing blood testing with no hassles, no delays, and no instrument. These devices will be deployed in Emergency Departments (EDs), clinics, and eventually the home.

Xip Diagnostics Founder and CEO Dr. Octavian Florescu spun out the company to commercialize research discoveries...

Totality Biosciences

Brief Description

Totality Biosciences is producing plant-based human milk oligosaccharides (HMOs), a high-value bioactive found in human breast milk. The breast milk substitute promises to improve nutrition in infant formula. The company also intends to supply complex HMOs for research and development of therapeutics.

Inventors

Patrick Shih, Collin Robert E. Barnum

Company Founders

Patrick Shih

Timeline

2025. Company founded

Sift Biosciences

Brief Description

Sift Biosciences supercharges existing cancer therapies by leveraging artificial intelligence and high-throughput cellular screening to discover and design immunotherapy boosters that significantly extend cancer patient survival. The company was co-founded by Yue Clare Lou (BS ’18 Microbial Biology; PhD ’23 Microbiology) and Maddie Williams (PhD student '23-present, Molecular & Cell Biology) to commercize technology developed during their doctoral research at UC Berkeley.

Inventors

Yue "Clare" Lou, Madeline Dee Williams

Company Founders

Yue "Clare" Lou (...

Shrink Technologies, Inc.

Brief Description

Shrink Technologies, Inc., based in Carlsbad, California, was acquired by Shrink Nanotechnologies, Inc. on May 29, 2009. Shrink Technologies specializes in developing innovative technologies, particularly focused on metal-enhanced fluorescence (MEF) applications. Their MEF technology, which integrates rapid prototyping methods with metal-fluorescence enhanced immunoassays, significantly enhances the sensitivity of diagnostic assays, making it possible to detect interactions that current methods miss. This technology has broad applications in drug discovery,...

Redwood Bioscience Inc.

Brief Description

Redwood Bioscience, Inc. develops a protein-chemical engineering technology to produce antibody-drug conjugates and other semi-synthetic biotherapeutics. The company offers SMARTag site-specific protein modification and cytotoxin-linker technologies that enable the generation of homogenous bioconjugates engineered to enhance potency, safety, and stability. Its SMARTag platform provides precise payload positioning and defined stoichiometry of payload-protein ratios. The company was incorporated in 2008 and is based in Emeryville, California. Redwood Bioscience, Inc....