IPIRA Startups

IPIRA Startups

Silicon Clocks, Inc.

Brief Description

Silicon Clocks was founded in 2006 to develop high performance semiconductor timing and sensor designs and its patented CMEMS technology. Silicon Clocks was backed by leading venture investors including Tallwood Venture Capital, Charles River Ventures, Formative Ventures, Lux Capital and Silicon Labs.

The company was co-founded by Dr. Roger Howe, former co-director of the Berkeley Sensor and Actuator Center and UC Berkeley Professor of Electrical Engineering, and BSAC post-doctoral researcher Emmanuel Quevy.

Silicon Clocks Inc. was...

nEye.ai

Brief Description

nEye.ai is a next-generation optical switch company. Their MEMS-based silicon photonics optical circuit switches (OCS) eliminate critical bottlenecks in AI processing by enabling direct optical connections among thousands of GPUs and memory units. The company's SuperSwitch is an ultra-low power consumption, high radix, compact chip-scale design, offering hyperscale data centers enhanced performance, efficiency, and scalability.

UC Berkeley Professor of Electrical Engineering and Computer Sciences, and Co-Director of Berkeley Sensor and Actuator Center and Berkeley...

Inapill

Brief Description

Inapill is developing novel therapeutics that tune immune cell metabolism (immunometabolism) to treat diseases caused by immune system overactivation and excessive inflammation.

The company was co-founded by Greg Timblin and Josh Farahzad. CEO Timblin earned his Ph.D. in Molecular & Cell Biology from UC Berkeley in 2014, in the labs of Professors Mark Schlissel and Robert Tjian. He also served as a postdoctoral fellow in Professor Kaoru Saijo’s lab at UC Berkeley, and then in Professor Val Weaver’s lab at UCSF.

Inventors

Kaoru Saijo, Greg Timblin...

Stylus Medicine

Brief Description

Stylus Medicine has created a new gene editing technology based on viral proteins called recombinases. These proteins naturally insert large swaths of DNA into bacterial genomes, but Stylus used machine learning to design recombinases that target specific regions of the human genome. The method is based on the pioneering work of Patrick Hsu, UC Berkeley assistant professor of bioengineering and co-founder and a core investigator of the Arc Institute. The company is on a mission to develop next-generation therapies for disease through genome engineering and chromatin...

EditPep, Inc.

Brief Description

CRISPR therapies enabled by a simple, potent delivery platform. The biotechnology company creates a class of peptides capable of delivering CRISPR enzymes into clinically-relevant and previously untransfectable cell types, enabling clients to get CRISPR therapies.

Inventors

Ross Wilson, Dana Foss, Alexander Marson, Srishti Sahu, David-Huy Nguyen, John Hunsinger, Daniel Carr

Company Founders

Dana Foss (UC Berkeley postdoc 2017-2022), UC Berkeley Assistant Adjunct Professor of Molecular Therapeutics Ross Wilson

Timeline 2021...

Two Blades Foundation

Brief Description

2Blades was established as a 501(c)3 charitable organization to implement practical uses of important innovations in plant science that address the rising incidence of crop disease. Working together with world leading scientists in plant-pathogen interactions, 2Blades has scouted and supported the most significant advances in the understanding of plant disease and immunity, as well as enabling technologies to develop disease resistant crops.

Remarkable advances have been realized in plant science over the past twenty years, including genome sequencing,...

QSX Bio

Brief Description

Developing medical therapeutics and vaccines through biosynthesis of natural compounds in plants.

Inventors

Jay Keasling, Yuzhong Liu, Henrik Scheller, Xiaoyue Chen, Samantha Aiko Crowe, James Reed, Laetitia Martin, Graham Arthur Hudson, Fei Gan

Company Founders

Yuzhong Liu

Timeline 2025. Company founded

Vivere Oncotherapies

Brief Description

Gene and cell therapies for cancer.

Inventors

Adam Schieferecke, John Dueber, David Schaffer, Juan Eduardo Hurtado, Hyun-Cheol Lee

Company Founders

Wanichaya Noiwangklang, Adam Schieferecke (UC Berkeley, Ph.D., Doctor of Philosophy, Mollecular and Cellular Biology), Juan Hurtado, Hyuncheol Lee, David Schaffer, John Dueber

Timeline 2024. Company founded.

Avista Therapeutics

Brief Description

Avista Therapeutics develops innovative gene therapies for retinal diseases, including rare ophthalmic conditions that have a profound impact on quality of life. The company leverage a computationally guided scAAVengr platform to generate and validate a toolkit of proprietary AAV vectors. A quantitative, in vivo-based approach and clinical ophthalmology expertise allows Avista Therapeutics to rapidly translate new gene therapies to the clinic.

Inventors

Stephen Graf Brohawn, Hillel Adesnik, Madeline McCloud

Company Founders

Leah Byrne (UC Berkeley PhD, 2007...

DNA Nanobots, LLC

Brief Description

DNA Nanobots is focused on developing the next generation of targeted nanomedicines and reshaping gene therapy by delivering genes previously considered undeliverable. Utilizing precise DNA self-assembly (DNA origami), the company engineers nanobots designed to carry and release therapeutic payloads directly to diseased cells with unprecedented specificity, minimizing systemic toxicity, and maximizing treatment efficacy.

Inventors

Jennifer Doudna, Enrique Lin Shiao, Rachael Lew

Company Founders

Patrick Halley, Christopher Lucas, Carlos Castro, Adel Mikhail...