Medical Therapeutics

Iris Micromedical, Inc.

Brief Description

Drug delivery based on microstructural devices that administer therapeutic agents to selected target sites for treatment.

Iris Micromedical was focused on the development of UC Berkeley Associate Professor of Engineering Mauro Ferrari's silicon particulate technology for the intravascular targeted treatment of cancer imedd.

Four years after founding Iris Micromedical, Dr. Ferrari moved to Ohio State University as a professor of bioengineering, internal medicine, and mechanical engineering, and reformed the company as IMedd, Inc.

Timeline 1995....

Intellia

BRIEF DESCRIPTION Intellia is a leading genome editing company focused on the development of proprietary, potentially curative therapeutics utilizing a recently developed biological tool known as the CRISPR/Cas9 system. Intellia leverages leading scientific expertise, clinical development experience, and intellectual property position to unlock broad therapeutic applications of CRISPR/Cas9 genome editing and develop a potential new drug class. Timeline 2014. Company founded. INVENTOR Jennifer Doudna

CalGen Therapeutics

Brief Description

Developer of a therapeutic inhaled antisense technology designed to prevent and treat respiratory infections.

Timeline 2021. Company founded Inventors

Kasper Karstensen, Sakari Kauppinen, Anders Michael Naar, Chi Zhu

Biotock

Brief Description

Development of treatments for age-related macular degeneration, a leading cause of blindness.

Timeline 2022. Company founded Inventors

Monika Maria Haoui, Polina Lishko

AsparaGlue

Brief Description

AsparaGlue has developed a superglue-like medical adhesive for external wound closure and internal tissue adhesion. The proprietary technology is the world’s only biocompatible and biodegradable medical superglue.

Timeline 2023. Company founded; joined Berkeley Skydeck accelerator, cohort 16 Inventors

Philip Messersmith, Subhajit Pal, Ji Soo Shin, Kelsey Gray DeFrates

Apertor Pharmaceuticals

Brief Description

Apertor creates novel molecular glues for therapeutic applications in multiple disease areas. The company applies a world-class synthetic biology platform using non-model organisms, a deep knowledge of complex natural products relevant to human health, and a computational pipeline enabled by structure-guided design. The result is a first-in-class approach to solving important pharmacological problems and delivering new, high-value treatment options for patients. The company was co-founded by UC Berkeley Professor of Chemical & Biomolecular Engineering and of...

Chiron Corporation

Brief Description

Chiron Corporation was an American biotechnology company engaged in biopharmaceuticals, vaccines and blood testing.

Timeline 1981. Company founded 1990. Company Initial Public Offering on NASDAQ under the ticker symbol of CHIR. 2006. Acquired by Novartis Inventors

Henry Chang, Felix Karim, Gerald Rubin, Marc Therrien, David Wassarman

Cell-X

Brief Description

Editing T-cells with nanopore-electroporation to improve CRISPR-Cas9 editing capabilities.

Timeline 2021. Company founded Inventors

YuHong Cao, Jennifer Doudna, Enbo Ma, Peidong Yang

4D Molecular Therapeutics LLC

Brief Description 4D Molecular Therapeutics is a global leader in gene therapy product research & development using scientific innovation to unlock the full potential of gene therapy for patients with genetic diseases. Their robust discovery platform, termed Directed Vector Evolution, empowers us to create customized gene delivery vehicles (novel AAV vectors) to deliver genes to any tissue or organ in the body. These customized products allow us to deliver normal genes to tissues with defective genes (as occurs in genetic diseases). This 4DMT discovery technology was originally developed...

Epigenetic Gene Editing

Brief Description

Epigenetic Gene Editing is a gene editing tools company dedicated to improvements in CRISPR-Cas9 editing by providing a fusion protein kit to gene editing companies.

Formerly known as EPI-CRISPRx.

Timeline 2021. Company founded Inventors

Enrique Lin Shiao, Jennifer Doudna