SBIR/STTR Recipient

Ansa Biotechnologies

Brief Description

With synthetic DNA fueling innovation in biological research, therapeutics, diagnostics, and biomanufacturing, there is an urgent need for faster and more accurate DNA synthesis. Currently, DNA is manufactured via a chemical method that has remained essentially unchanged for 35 years and has approached a plateau. Ansa Biotechnologies is developing a faster, more accurate, and cleaner enzyme-based DNA synthesis technology. The technique promises to dramatically accelerate innovation in biological research and engineering.

The approach is based on polymerase-...

Acrigen Biosciences, Inc.

Brief Description

Acrigin Biosciences is developing Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics. Acrigen’s proprietary technology leverages novel αCas and μCas CRISPR gene editors coupled with ErAcrs (engineered anti-CRISPR proteins) to create an editing toolbox with best-in-class efficiency and precision. The company's technology will expand the impact of CRISPR by improving the efficacy and safety of novel gene editing therapies.

Inventors

Jennifer Doudna, Christof Fellmann, Haridha Shivram, Kyle Watters

Company Founders

David...

Magnetic Tides

Brief Description

Magnetic Tides has developed a new non-invasive brain stimulation (NIBS) system capable of modulating brain function more reliably and effectively than previously existing NIBS methods.

NIBS is used as a research tool to safely, transiently alter the excitability state of targeted neurons when testing causal hypotheses about brain-behavior relationships. In addition, clinicians have recognized the potential of NIBS as a new intervention in the treatment of neurological and psychiatric disorders.

Timeline 2019. Company founded Inventors

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Valitor Inc.

Brief Description

Valitor, Inc. has developed novel methods of modifying therapeutic proteins to achieve substantial control over their pharmacokinetics, target specificity, and bioactivity. The company's technology platform can be broadly applied to improve the pharmacological properties of many protein drugs that are currently approved or under development. The lead product will be used to improve the treatment of diseases in ophthalmology. The company also has development pipelines for oncology and orthopedics products.

The company was incubated at Berkeley Skydeck, UC Berkeley's...

SirenOpt

Brief Description

SirenOpt provides manufacturing intelligence solutions that accelerate research and development and enable cost-effective manufacturing of high-performance micro- and nano-materials, including lithium-ion batteries, membranes, semiconductors, flexible electronics, packaging materials, and many others. The company's real-time manufacturing intelligence platform, designed for cost-effective manufacturing of thin films, utilizes cold atmospheric plasma and physics-informed machine learning to collect critical manufacturing data and improve manufacturing quality and output....

Algen Biotechnologies

Brief Description

Algen Biotechnologies is building a next-generation, functional genomics-based platform for the discovery of novel therapeutics for cancers with high unmet need. Algen’s research group focuses on developing and applying novel functional genomics technologies to address scientific challenges in drug discovery. The company's biologists and data scientists are collaborating to deliver innovative, patient-centric medicines for the toughest-to-treat diseases.

The company was founded to commercialize technology developed at UC Berkeley while Algen Biotechnologies CEO...

ReRx Therapeutics

Brief Description

ReRx is developing novel oral therapeutics to treat patients with severe metabolic diseases including obesity, metabolic syndrome, diabetes, and liver diseases. The company's therapeutics target metabolic pathways involved in regulating energy homeostasis and improve treatment outcomes compared to similar pharmacological agents.

Timeline 2023. Company founded; Joins Berkeley Skydeck Cohort 17 Inventors

Chi Zhu, Anders Michael Naar, Justin Yu-Sun Lee

suitX

Brief Description

suitX brought advanced accessible exoskeletons to industrial and medical markets with funding from venture capital, industry, and government.

Formerly known as U.S. Bionics.

Acquired by Ottobock in 2021.

Inventors

Homayoon Kazerooni, Adam Zoss, Andre Nguyen Van Qui, Bradley Perry, Christina Yee, Daniel Merala, David Cuban, Dong-Jin Hyun, Dylan Fairbanks, Erich Hacker, Han Woong Bae, James Alden Hatch, Jason Reid, JiaLong James Ren, Jing Song Huang, JJ Kuwata, John Wilkey, Jon Burns, Katherine Fearing, Katherine Strausser, Kibeum Ryoo, Kyunam Kim, Lace...

Mosaic Materials

Brief Description

Mosaic Materials is dedicated to reducing the cost and environmental impact of fossil fuels through the application of proprietary, highly efficient gas separation technologies. The company utilizes porous solids known as metal-organic frameworks to selectively remove impurities such as CO2 from gas mixtures in an array of applications from submarines to power plants.

The company was acquired by Baker Hughes (NAS: BKR) in 2022.

Inventors

Gokhan Barin, Deanna D'Alessandro, Stephen Geier, Zoey Herm, Matthew Kapelewski, Rajamani Krishna, Jeffrey Long, Thomas...

Chirp Microsystems, Inc.

Brief Description

Chirp Microsystems, Inc. designs, develops, and manufactures a line of extremely low power, ultrasonic 3D-sensing solutions for consumer electronics, smart homes, industrial automation, and much more. The company's ultrasonic 3D-sensing systems offer millimeter-accurate range information, based on machine learning and neural network algorithms and outperform infrared-based alternatives by every metric in real-world applications like consumer electronics, smart homes and industrial automation, enabling clients to avail the always-on sensing for...